Structure | Cat No. | Product Name | CAS No. | Product Description |
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V4573 | (4E)-SUN9221 | 222318-55-0 | (4E)-SUN9221 is a potent α1-adrenergic receptor and 5-HT2 receptor blocker (antagonist) with anti-hypertensive (blood pressure lowering) and antiplatelet aggregation effects. |
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V4720 | (±)-BI-D | 1416258-16-6 | (±)-BI-D is a novel and potent allosteric/noncatalytic site integrase inhibitor that binds integrase at the LEDGF/p75 binding site. |
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V5159 | L 601920-0 (Methyl-3β-hydroxycholenate) | 20231-57-6 | Methyl-3β-hydroxycholenate is a ROR gamma modulator. |
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V4605 | 5Z-7-Oxozeaenol | 253863-19-3 | 5Z-7-Oxozeaenol, a natural anti-protozoan compound isolated from fungae, is a novel, potent irreversible / covalent and selective inhibitor ofTAK1andVEGF-R2withIC50s of 8 nM and 52 nM, respectively. |
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V4657 | A-437203 | 220519-06-2 | A-437203 is a novel, potent and selectiveD3receptor antagonist withKiof 71, 1.6, and 6220 nM for D2, D3, and D4receptors, respectively. |
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V4566 | ABBV-4083 | 1809266-03-2 | ABBV-4083, a Tylosin A analog withimprovements in anti-Wolbachiaand anti-filarial activity and oral pharmacokinetic properties, is a novel macrofilaricidal agent which acts by targeting the worm-symbiont Wolbachia bacterium. |
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V4690 | ACY-1083 | 1708113-43-2 | ACY-1083 is a novel, potent, selective and brain-penetrant HDAC6 inhibitor with an IC50 of 3 nM. |
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V4689 | ACY-957 | 1609389-52-7 | ACY-957 is a novel, potent and selective inhibitor ofHDAC1andHDAC2isoforms withIC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively. |
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V4985 | Ajulemic acid | 137945-48-3 | Ajulemic acid (also known as lenabasum) is a cannabinoid CB2 receptor agonist with the potential for treatment of skin-predominant dermatomyositis. |
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V4738 | AMG2850 | 1470018-52-0 | AMG2850 is a novel, potent, orally bioavailable and selectivesmall molecule antagonist oftransient receptor potential melastatin 8 (TRPM8). |
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V4846 | AMY-101 | 1427001-89-5 | AMY-101 (also known as Cp40) is a peptidic inhibitor of the central complement component C3. |
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V5051 | ANT431 | 1639972-90-9 | ANT431 is a novel and potent inhibitor of metallo-β-lactamase with the potential for the treatment of carbapenem-resistant enterobacteriaceae infections. |
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V4565 | ARN 077 | 1373625-34-3 | ARN 077 (ARN-077) is a novel, potent and selectiveN-acylethanolamine acid amidase (NAAA)inhibitor with anIC50of 7 nM for human NAAA. |
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V4991 | AZD3147 | 1101810-02-9 | AZD3147 (AZD-3147) is an highly potent and selective dual inhibitor of mTORC1/2 with IC50 of 1.5 nM. |
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V4982 | AZD3458 (PI3Kγ inhibitor 3) | 2132961-46-5 | AZD-3458 (PI3Kγ inhibitor 3) is a novel, potent, orally bioavailable and highly isoform selectivePI3Kγinhibitor with anticancer activity. |
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V4601 | Bamirastine | 215529-47-8 | Bamirastine (also known as TAK-427),a new imidazopyridazine derivative, is a novelantihistamine compound withantiallergic effects. |
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V4993 | BEBT-908 | 1235449-52-1 | BEBT-908,extracted from patent US/20120088764A1, Compound example 243, is a novel, potent and selectivePI3Kαinhibitor with anIC50<0.1 μM, it also inhibits HDAC with 0.1 μM≤IC50≤1 μM. |
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V4519 | BGB-102 | 807640-87-5 | JNJ-26483327 (also known as BGB102; JNJ26483327; BGB-102) is a novel, potent, reversible and orally bioavailable small-molecule multitargeted tyrosine kinase inhibitor againstEGFR,HER2, andHER4withIC50s of 9.6 nM, 18 nM and 40.3 nM, respectively. |
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V4702 | BI-0252 | 1818291-27-8 | BI-0252 is a novel, potent, highly selective, orally bioactiveMDM2-p53interaction inhibitor with anIC50of 4 nM. |
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V4714 | BI-1408 | 2231075-94-6 | BI-1408, atetrahydroindazole derivative, is a novel,centrally efficacious and potentγ secretasemodulator with anIC50of 0.04 μM forAβ42. |