New7

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

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New7

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V4573	(4E)-SUN9221	222318-55-0	(4E)-SUN9221 is a potent α1-adrenergic receptor and 5-HT2 receptor blocker (antagonist) with anti-hypertensive (blood pressure lowering) and antiplatelet aggregation effects.
V4720	(±)-BI-D	1416258-16-6	(±)-BI-D is a novel and potent allosteric/noncatalytic site integrase inhibitor that binds integrase at the LEDGF/p75 binding site.
V4605	5Z-7-Oxozeaenol	253863-19-3	5Z-7-Oxozeaenol, a natural anti-protozoan compound isolated from fungae, is a novel, potent irreversible / covalent and selective inhibitor ofTAK1andVEGF-R2withIC50s of 8 nM and 52 nM, respectively.
V4657	A-437203	220519-06-2	A-437203 is a novel, potent and selectiveD3receptor antagonist withKiof 71, 1.6, and 6220 nM for D2, D3, and D4receptors, respectively.
V4566	ABBV-4083	1809266-03-2	ABBV-4083, a Tylosin A analog withimprovements in anti-Wolbachiaand anti-filarial activity and oral pharmacokinetic properties, is a novel macrofilaricidal agent which acts by targeting the worm-symbiont Wolbachia bacterium.
V4690	ACY-1083	1708113-43-2	ACY-1083 is a novel, potent, selective and brain-penetrant HDAC6 inhibitor with an IC50 of 3 nM.
V4689	ACY-957	1609389-52-7	ACY-957 is a novel, potent and selective inhibitor ofHDAC1andHDAC2isoforms withIC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively.
V4985	Ajulemic acid	137945-48-3	Ajulemic acid (also known as lenabasum) is a cannabinoid CB2 receptor agonist with the potential for treatment of skin-predominant dermatomyositis.
V4738	AMG2850	1470018-52-0	AMG2850 is a novel, potent, orally bioavailable and selectivesmall molecule antagonist oftransient receptor potential melastatin 8 (TRPM8).
V5074	Amrubicin HCl (Calsed)	92395-36-3	Amrubicin HCl (also known as SM-5887 hydrochloride), a third-generation synthetic 9-amino-anthracycline, is a potent DNAtopoisomerase IIinhibitor with antineoplastic activity.
V4846	AMY-101 acetate	1427001-89-5	AMY-101 (also known as Cp40) is a peptidic inhibitor of the central complement component C3.
V5051	ANT431	1639972-90-9	ANT431 is a novel and potent inhibitor of metallo-β-lactamase with the potential for the treatment of carbapenem-resistant enterobacteriaceae infections.
V5028	Arfolitixorin	31690-11-6	Arfolitixorin, an intravenously administered folate-based compound,is a novel and potent antifolate modulator that isbeing developed by Isofol Medical AB, for the treatment of cancer.
V4565	ARN 077	1373625-34-3	ARN 077 (ARN-077) is a novel, potent and selectiveN-acylethanolamine acid amidase (NAAA)inhibitor with anIC50of 7 nM for human NAAA.
V4903	Arzoxifene HCl	182133-27-3	Arzoxifene (also known as LY353381) is a novel, potent, synthetic aromatic derivative, and selectiveestrogen receptorantagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol.
V5005	Atrial Natriuretic Peptide (ANP) (1-28)	89213-87-6	Carperitide [SUN4936; SUN-4936;Atrial Natriuretic Peptide (ANP) (1-28), novel human, porcine] is an endogenous 28-amino acid hormone produced/ecreted by the human heart in response to cardiac injury and mechanical stretch.
V4991	AZD3147	1101810-02-9	AZD3147 (AZD-3147) is an highly potent and selective dual inhibitor of mTORC1/2 with IC50 of 1.5 nM.
V4982	AZD3458 (PI3Kγ inhibitor 3)	2132961-46-5	AZD-3458 (PI3Kγ inhibitor 3) is a novel, potent, orally bioavailable and highly isoform selectivePI3Kγinhibitor with anticancer activity.
V4732	Balamapimod	863029-99-6	Balamapimod (formerly also known as MKI-833) is a novel, potent, and reversible Ras/Raf/MEK inhibitor.
V4601	Bamirastine	215529-47-8	Bamirastine (also known as TAK-427),a new imidazopyridazine derivative, is a novelantihistamine compound withantiallergic effects.