| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V3220 | ML239 | 1378872-36-6 | ML239 was originally identified as a potent and selective inhibitor of breast cancer stem cells with an IC50of 1.16 μM, but recent studies (2016 Nature 12(2):109-16. |
|
V3235 | ML329 | 19992-50-8 | ML329 is a potent small molecule inhibitor ofMITF (Micropthalmia-associated transcription factor) which inhibits TRPM-1 (melastatin, a MITF target gene) promoter activity with anIC50of 1.2 μM. |
|
V3353 | MRK-016 | 783331-24-8 | MRK-016 (MRK016; MRK 016) is a novel, potent, orally bioactive and selective negative allosteric modulator (inverse agonist) of α5 subunit-containing GABAA with nootropic properties. |
|
V3169 | Netarsudil (AR-13324) | 1254032-66-0 | Netarsudil (formerly known as AR-13324; AR13324; trade name Rhopressa) is ROCK inhibitor approved in 2017 for the treatment of glaucoma and ocular hypertension. |
|
V3133 | Norcantharidin | 5442-12-6 | Norcantharidin (also known as NCTD; Endothall anhydride, Norcantharadine) is a dual inhibitor ofc-Met and EGFR with anticancer activity. |
|
V3275 | NSC23005 | 6314-70-1 | NSC23005 is a novel and potentp18inhibitor withED50of 5.21 nM in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models. |
|
V3274 | NSC23005 sodium | 1796596-46-7 | NSC23005 sodium is a novel and potentp18inhibitor withED50of 5.21 nM in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models. |
|
V3216 | PF-06260933 2HCl | 1883548-86-4 | PF-06260933 is a highly selective small-molecule inhibitor ofMAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) withIC50values of 3.7 and 160 nM for cell-freel assay (kinase) and cell assay, respectively. |
|
V3112 | PF-06651600 (Ritlecitinib) malonate | 2140301-97-7 | Ritlecitinib (PF06651600;PF-06651600) malonate, themalonate salt ofPF 06651600, is an irreversibleJAK3inhibitor with anti-inflammatory activity. |
|
V2948 | PF-3274167 | 900510-03-4 | Cligosiban (formerly known as PF-3274167) is a novel, potent, selective and high-affinity nonpeptideantagonist of oxytocin receptor(OTR) with Ki of 9.5 nM. |
|
V2947 | PF-915275 | 857290-04-1 | PF-915275 (PF915275) is a novel and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11betaHSD1) with Ki of<1 nM and good pharmacokinetics.11betaHSD1 play a key role in ligand-induced activation of the GR through the production of cortisol. |
|
V3311 | PZ-2891 | 2170608-82-7 | PZ-2891 (PZ2891) is an orally bioavailable, and brain penetrant allosteric activator of Pantothenate kinase (PANK) with neuroprotective activity. |
|
V2955 | Ro 48-8071 fumarate | 189197-69-1 | Ro 48-8071 fumarate is an orally bioavailable inhibitor of OSC (Oxidosqualene cyclase) with IC50of ~6.5 nM. |
|
V3185 | TAK-659 2HCl | 1312691-41-0 | TAK-659 2HCl (TAK659 dihydrochloride) is a novel, potent, highlyselective and orally bioavailable spleen tyrosine kinase (Syk) inhibitor with anticancer effects. |
|
V3372 | Tirasemtiv | 1005491-05-3 | Tirasemtiv (also known as CK2017357) is a novel small-molecule activator of fast-skeletal-troponin, it is being developed as a potential treatment for diseases and conditions associated with aging, muscle weakness and wasting or neuromuscular dysfunction. |
|
V3021 | UNC1079 | 1418741-86-2 | UNC1079, the piperidine analog of UNC1021, is a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. |
|
V3265 | Cebranopadol hemicitrate | 863513-92-2 | Cebranopadol hemicitrate, the hemicitrate salt ofCebranopadol (also known as GRT-6005), is a novel, first in class compound with potent agonist activity on ORL-1 (opioid receptor like -1) and the well established mu opioid receptor. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
