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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
CRX-547 V50916 CRX-547 216014-05-0 lipid A mimetic
CTP-NBD V82217 CTP-NBD 1268513-27-4 CTP-NBD is a cell-penetrating/penetrable and specific NFκB inhibitor.
Cyanine 7-amine chloride hydrochloride V91336 Cyanine 7-amine chloride hydrochloride 1650559-73-1 Cyanine 7-amine (chloride hydrochloride) can be used to label cationic nanoparticles (NP) or cationic NP conjugates (NPCs), and can track the residence time and clearance of nanoparticles in the body.
D-Lin-MC3-DMA V20104 D-Lin-MC3-DMA 1224606-06-7 D-Lin-MC3-DMA is a potent andionizable / cationic lipid that has been used for synthesis of lipid nanoparticles (LNPs, gene vector) to deliver siRNA.
DC-6-14 V90423 DC-6-14 107086-76-0 DC-6-14 is a cationic lipid with gene transfection activity and can be used in the synthesis of liposomes.
DGDG V73410 DGDG 63142-69-8 DGDG, a chloroplast lipid, is a bilayer-forming lipid.
DGTS V91043 DGTS 1607456-57-4 DGTS is a structural isomer of DGTA and one of the most common betaine lipids in microalgae.
di-Pal-MTO V73485 di-Pal-MTO 1349197-90-5 di-Pal-MTO is a palm oil-based lipid produced by combining the anti-cancer active molecule mitoxantrone (MTO) with palmitoleic acid.
Diamino lipid DAL4 V73437 Diamino lipid DAL4 2939000-43-6 Diamino lipid DAL4 is a new type of lipid nanoparticles (LNPs) that can encapsulate mRNA encoding cytokines such as IL-12, IL-27 and GM-CSF.
Dicamba-(CH2)5-acid V82220 Dicamba-(CH2)5-acid 2892008-07-8 Hapten Dca is an immune hapten.
Dielaidoylphosphatidylethanolamine (DEPE) V73476 Dielaidoylphosphatidylethanolamine (DEPE) 16777-83-6 Dielaidoylphosphatidylethanolamine is a liposome used to deliver active molecules.
Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) V74064 Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) 3700-67-2 Dimethyldioctadecylammonium bromide is a synthetic cationic lipid widely used in gene delivery and vaccine development.
Dios-Arg diTFA V83445 Dios-Arg diTFA 1807353-31-6
Distearoylphosphatidylserine sodium V87565 Distearoylphosphatidylserine sodium 321595-13-5 Distearoylphosphatidylserine sodium is an anionic phospholipid with a stearic acid tail (18:0) and a carboxylic acid (COOH) and an amine (NH2) in its head group.
DLin-K-C3-DMA V74066 DLin-K-C3-DMA 1217306-46-1 DLin-K-C3-DMA is a cationic lipid that may be utilized in the synthesis/preparation of nucleic acid lipid particles to deliver nucleic acids.
DLin-KC2-DMA V20103 DLin-KC2-DMA 1190197-97-7 DLin-KC2-DMA is novel ionizable and cationic lipid useful for siRNA delivery.
DLin-M-C4-DMA V73439 DLin-M-C4-DMA 1226909-66-5 DLin-M-C4-DMA (Compound MC4) is a cationic lipid.
DLinDMA V20102 DLinDMA 871258-12-7 DLinDMA (1,2-dilinoleyloxy-3-dimethylaminopropane) is anionizable cationic lipid used for siRNA delivery.
DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) V74056 DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) 18194-25-7 DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists.
DLPG V90355 DLPG 73548-69-3 DLPG is a phospholipid with lauric acid (a 12-chain fatty acid) inserted at the sn-1 and sn-2 positions, and its phosphate group is linked to glycerol.
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