Almost all living things contain potassium channels, which are the most common type of ion channel. They build pores across cell membranes that are selective for potassium. The majority of cell types contain potassium channels, which regulate a wide range of cellular activities. Potassium channels work to quickly and selectively conduct potassium ions down their electrochemical gradient. In many cells, these channels function to either set or reset the resting potential. The delayed counterflow of potassium ions in excitable cells, like neurons, shapes the action potential. Failure of potassium channels can lead to potentially fatal arrhythmias by helping to control the duration of the action potential in cardiac muscle. Maintaining vascular tone may also involve potassium channels.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V92122 | BML264 | 99196-74-4 | BML264 ((E)-N-(p-amylcinnamoyl) anthranilic acid) is a TREK-1 agonist. |
|
V78491 | BmP02 | BmP02 is a selective Kv1.3 channel blocker and selective Kv4.2 modulator extracted from the venom of the Chinese scorpion (Buthus martensi Karsch). | |
|
V3481 | BMS-191095 | 166095-21-2 | BMS-191095 is a novel and potent activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels. |
|
V103289 | BMS-191095 hydrochloride | 166095-95-0 | BMS-191095 hydrochloride is a mitochondrial KATP channel opener that can protect the myocardium without causing vasodilation or affecting electrophysiology. It exerts a cardioprotective effect by prolonging the myocardial contraction time during ischemia, improving contractile function after reperfusion, and reducing the release of lactate dehydrogenase (LDH). |
|
V87217 | BMS-986308 | 2254333-97-4 | BMS-986308 is a selective and orally active renal extramedullary potassium (ROMK) channel inhibitor. |
|
V73595 | Cesium chloride | 7647-17-8 | Cesium chloride is a potassium channel inhibitor. |
|
V77154 | Charybdotoxin TFA | Charybdotoxin TFA is a 37-amino acid (AA) peptide that is a K+ channel blocker. | |
|
V73646 | Chlorahololide C | 1007859-25-7 | Chlorahololide C is a lindane sesquiterpene dimer extracted from Chloranthus holostegius. |
|
V73636 | Chlorahololide D | 943136-39-8 | Chlorahololide D is a potent and specific Potassium Channel blocker with IC50 of 2.7 μM. |
|
V73596 | Chromanol 293B | 163163-23-3 | Chromanol 293B selectively blocks slow delayed rectifier potassium currents (IKs) with IC50 of 1-10 μM and is a weak inhibitor of KATP channels. |
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V73601 | Cibenzoline (Cifenline; Ro 22-7796) | 53267-01-9 | Cibenzoline is a potent KATP channel inhibitor that directly affects the pore-forming Kir6.2 subunit but not the SUR1 subunit. |
|
V101512 | Cibenzoline succinate | 100678-32-8 | Cifenline succinate is Cifenline succinate. |
|
V103447 | cis-KV1.3-IN-1 | 3052324-05-4 | cis-KV1.3-IN-1 (compound cis-18) is the cis isomer of KV1.3-IN-1. |
|
V73605 | Clamikalant sodium (HMR 1098) | 261717-22-0 | Clamikalant sodium (HMR 1098) is a non-selective and ATP-sensitive potassium (KATP) channel blocker. |
|
V73631 | Clobutinol | 14860-49-2 | Clobutinol is a compound that has antitussive effects. |
|
V73584 | Clobutinol hydrochloride | 1215-83-4 | Clobutinol HCl Clobutinol is a compound with antitussive effects. |
|
V18559 | CLP-290 | 1181083-81-7 | CLP-290 is a novel and potent KCC2 modulator acting as a prodrug of CLP-257, and is highly selective for KCC2 over related Cl- transporters. |
|
V87214 | CPK20 | 2397708-22-2 | CPK20 is a potent and highly selective KCNT1 channel blocker and can be used in epilepsy research. |
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V79006 | DAD | DAD is an ion channel blocker that blocks voltage-gated potassium channels and is a third-generation photoswitch that responds to visible light. | |
|
V78641 | DAD dichloride | DAD dichloride is an ion channel blocker (blocks voltage-gated potassium channels) and a third-generation photoswitch that responds to visible light. |
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