Almost all living things contain potassium channels, which are the most common type of ion channel. They build pores across cell membranes that are selective for potassium. The majority of cell types contain potassium channels, which regulate a wide range of cellular activities. Potassium channels work to quickly and selectively conduct potassium ions down their electrochemical gradient. In many cells, these channels function to either set or reset the resting potential. The delayed counterflow of potassium ions in excitable cells, like neurons, shapes the action potential. Failure of potassium channels can lead to potentially fatal arrhythmias by helping to control the duration of the action potential in cardiac muscle. Maintaining vascular tone may also involve potassium channels.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V12383 | Minoxidil | 38304-91-5 | Minoxidil (U-10858; Loniten; Rogaine)is anantihypertensive agentand vasodilatorthat has also found usefulness in treatment of hair loss andalopecia areatawhenapplied topically. |
|
V3523 | Naminidil | 220641-11-2 | Naminidil (BMS 234303-01) is a novel and potentcyanoguanidineKATPopener (ATP-Sensitive Potassium Channel Vasodilator). |
|
V29291 | Vernakalant (RSD-1235) | 794466-70-9 | Vernakalant(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic. |
|
V25309 | Mesoridazine free base | 5588-33-0 | Mesoridazine is a potent phenothiazine dopamine receptor anatagonist that is able to inhibit D2DR and D4DR. |
![萘并[1,2-d]噻唑-2-胺](http://www.invivochem.com/upload/0201/6380932887685397841797710793.png)
|
V14863 | SKA-31 | 40172-65-4 | SKA-31 is a potassium channel activator. |
|
V0198 | Nateglinide (Starlix; A4166) | 105816-04-4 | Nateglinide (formerly A-4166; trade names: Fastic, Starlix), a meglitinide analog,is a potent and orally bioavailableantihyperglycemic medication used for treating type 2 diabetes [non-insulin-dependent diabetes mellitus (NIDDM)]. |
|
V3861 | Amifampridine | 54-96-6 | Amifampridine (trade name: Firdapse; pyridine-3,4-diamine, 3,4-diaminopyridine, 3,4-DAP) is an FDA approved drug used predominantly in the treatment of a number of rare muscle diseases such as Lambert-Eaton myasthenic syndrome (LEMS) in adults. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
