The role of tau as a microtubule-associated protein in neurons is well established. They play major roles in preserving the stability of microtubules in axons and are widely distributed in central nervous system (CNS) neurons. However, in a variety of neurodegenerative disorders collectively known as tauopathies, aberrant assembly of tau into insoluble aggregates is accompanied by synaptic dysfunction and neural cell death.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V70080 | Tau Peptide (307-321) | 330456-50-3 | Tau Peptide (307-321) is a bioactive peptide discovered by peptide screening. | |
V70100 | Tau Peptide (337-368) (Repeat 4 Domain) | 330456-27-4 | Tau Peptide (337-368) (Repeat 4 Domain) is a bioactive peptide discovered by peptide screening. | |
V70077 | Tau Peptide (379-408) | 1246357-53-8 | Tau Peptide (379-408) is a fragment of Tau protein. | |
V70095 | Tau Peptide (45-73) (Exon 2/Insert 1 Domain) | 2022956-54-1 | Tau Peptide (45-73) (Exon 2/Insert 1 Domain) is a fragment of Tau protein. | |
V70089 | Tau Peptide (512-525)amide | 2022956-61-0 | Tau Peptide (512-525) amide is a bioactive peptide discovered by peptide screening. | |
V70084 | Tau Peptide (74-102) (Exon 3/Insert 2 Domain) | 1322695-34-0 | Tau Peptide (74-102) (Exon 3/Insert 2 Domain) is a fragment of Tau protein. | |
V70075 | Tau protein (592-597), human TFA | 2703746-44-3 | Tau protein (592-597), human TFA is a polypeptide fragment of human Tau protein. | |
V70102 | Tau protein aggregation-IN-1 | 916179-45-8 | Tau protein aggregation-IN-1 (compound 0c) is a Tau protein aggregation inhibitor. | |
V84679 | TAU-IN-1 | 1383373-65-6 | ||
V70097 | TRV-1387 | 1569645-63-1 | TRV-1387 is a benzofuran that can inhibit the aggregation of tau and amyloid-β. | |
V70063 | TTBK1-IN-1 | 2735015-60-6 | TTBK1-IN-1 is a specific, brain-penetrating tau tubulin kinase 1 (TTBK1) inhibitor (antagonist) with IC50 of 2.7 nM. |