The three G-protein-coupled cannabinoid receptor subtypes currently recognized are central (CB1), peripheral (CB2), and GPR55. The majority of CB1 receptors are found at central and peripheral nerve terminals. CB2 receptors are mainly found in immune cells and non-neuronal tissues where they regulate cytokine release and cell migration. According to recent reports, the CNS may also express CB2 receptors. Non-CB1/CB2 receptors known as GPR55 show affinity for endogenous, botanical, and synthetic cannabinoids. Anandamide and 2-arachidonylglycerol are examples of endogenous ligands for cannabinoid receptors.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V4367 | TARANABANT | 701977-09-5 | Taranabant (aslo known as MK-0364) is a novel, highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist being investigated as a potential treatment for obesity due to its anorectic effects. |
|
V79660 | Trimethobenzamide-d6 (Ro 2-9578 (free base D6)) | Trimethobenzamide-d6 is the deuterated form of Trimethobenzamide. | |
|
V71559 | Vicasinabin (RG7774) | 1433361-02-4 | Vicasinabin (RG7774) is a potent agonist of cannabinoid receptor 2 (CB2). |
|
V2061 | WIN 55,212-2 Mesylate | 131543-23-2 | WIN 55,212-2 Mesylate is a novel and potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. |
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