Size | Price | Stock | Qty |
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5mg |
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10mg |
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50mg |
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100mg |
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Other Sizes |
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ln Vivo |
2-Methoxyidazoxan monohydrochloride (1 mg/kg) improves the ability of rats with neonatal ventral hippocampal lesion (NVHL) to move about in new settings. 2-The effects of 2-methylidazoxan monohydrochloride on locomotion are biphasic, exhibiting a reduction at first before intensification [3].
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References |
[1]. Head GA. Importance of imidazoline receptors in the cardiovascular actions of centrally acting antihypertensive agents. Ann N Y Acad Sci. 1995;763:531-540.
[2]. Trendelenburg AU, et al. Antagonists that differentiate between alpha 2A-and alpha 2D-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1996;353(3):245-249. [3]. Sandner G, et al. Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion. Front Behav Neurosci. 2014;8:15. Published 2014 Jan 28. |
Molecular Formula |
C12H15CLN2O3
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Molecular Weight |
270.71
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CAS # |
109544-45-8
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SMILES |
Cl[H].O1C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C1(C1=NC([H])([H])C([H])([H])N1[H])OC([H])([H])[H]
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Solubility (In Vitro) |
H2O: 100 mg/mL (369.40 mM)
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Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (184.70 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 3.6940 mL | 18.4699 mL | 36.9399 mL | |
5 mM | 0.7388 mL | 3.6940 mL | 7.3880 mL | |
10 mM | 0.3694 mL | 1.8470 mL | 3.6940 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.