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    Formestane (CGP-32349)
    Formestane (CGP-32349)

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    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V1801
    CAS #: 566-48-3Purity ≥98%

    Description: Formestane (formerly also known as CGP-32349, NSC 282175) is a second generation, selective, orally bioactive and synthetic steroidal aromatase inhibitor with an IC50 of 80 nM. Formestane is a substance with anticancer activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.

    References: Steroids. 2013 Nov;78(11):1103-9; Ann Oncol. 1994;5 Suppl 7:S19-24.

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    Molecular Weight (MW)302.41
    FormulaC19H26O3
    CAS No.566-48-3
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Solubility (In vitro)DMSO: 61 mg/mL (201.7 mM)
    Water: <1 mg/mL
    Ethanol:<1 mg/mL
    Other info
    Chemical Name: (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
    InChi Key: OSVMTWJCGUFAOD-KZQROQTASA-N
    InChi Code: InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1
    SMILES Code: O=C(C(O)=C1CC[[email protected]@]2([H])[[email protected]]3([H])CC4)CC[[email protected]]1(C)[[email protected]@]2([H])CC[[email protected]]3(C)C4=O 
    SynonymsCGP-32349, NSC282175; NSC-282175; NSC 282175; CGP32349; CGP 32349; CGP-32349; 4OHA; 4OHAD; Formestane; Lentaron.


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