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Adrenergic Receptor

Adrenergic Receptor

Adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine and epinephrine.These receptors are found on numerous cells, and when a catecholamine binds to one of these receptors, the sympathetic nervous system is typically stimulated. The fight-or-flight response, which entails dilating the pupils of the eyes, mobilizing energy, and rerouting blood flow away from skeletal muscle to non-essential organs, is controlled by the sympathetic nervous system.There are numerous subtypes of the two main groups of adrenergic receptors, and. The receptor subtypes 1 and 2 exist. There are three subtypes of receptors: 1, 2, and 3. They are all associated with Gs proteins, which are associated with adenylate cyclase. Thus, antagonist binding increases the level of the second messenger cAMP inside of the cell. The cAMP-dependent protein kinase (PKA), one of cAMP's downstream effectors, mediates some intracellular processes after hormone binding.

Adrenergic Receptor related products

Structure Cat No. Product Name CAS No. Product Description
(-)-Isoproterenol hydrochloride V101112 (-)-Isoproterenol hydrochloride 5984-95-2 (-)-Isoproterenol (L-isoproterenol; Proternol L) hydrochloride is a β-adrenergic receptor agonist.
(1R,2S)-Dihydrobupropion V116575 (1R,2S)-Dihydrobupropion 292055-72-2 (1R,2S)-dihydrobupropion is a norepinephrine-dopamine reuptake inhibitor and one of the active metabolites of bupropion.
(2S,3S)-Zenidolol hydrochloride V112149 (2S,3S)-Zenidolol hydrochloride 1236034-74-4 (2S,3S)-Zenidolol ((2S,3S)-ICI-118551) hydrochloride is a β2-adrenergic receptor (β2AR) antagonist with a pKi value of 7.51 for β1AR and 9.27 for β2AR.
(E)-8-Dodecenyl acetate V121757 (E)-8-Dodecenyl acetate 38363-29-0 (E)-8-Dodecenyl acetate is a sex pheromone that targets olfactory receptors in male golden moths and acts as an agonist.
(R)-Doxazosin V121921 (R)-Doxazosin 70918-17-1 (R)-Doxazosin is an isomer of doxazosin, a selective orally active α1-adrenergic receptor agonist.
(Rac)-Nebivolol-d2,15N V87631 (Rac)-Nebivolol-d2,15N (Rac)-Nebivolol-d2,15N is 15N and deuterium labeled (Rac)-Nebivolol.
(Rac)-Nebivolol-d4 hydrochloride ((Rac)-R 065824-d4 hydrochloride) V84080 (Rac)-Nebivolol-d4 hydrochloride ((Rac)-R 065824-d4 hydrochloride) 2701283-32-9
(Rac)-Norepinephrine-d3 formate V122030 (Rac)-Norepinephrine-d3 formate (Rac)-Norepinephrine-d3 formate is a deuterium-labeled norepinephrine.
(Rac)-Silodosin V122040 (Rac)-Silodosin 160970-64-9 (Rac)-Silodosin is the racemic form of silodosin.
(S)-Atenolol V101375 (S)-Atenolol 93379-54-5 (S)-Atenolol is a potent β-adrenergic receptor blocker.
(S)-Bopindolol V122150 (S)-Bopindolol 62697-41-0 (S)-Bopindolol is a β-adrenergic receptor blocker that can be used to prevent and inhibit muscle loss, functional loss, and/or decreased bone density caused by weight loss.
(S)-Doxazosin V113025 (S)-Doxazosin 104874-86-4 (S)-Doxazosin is a long-acting selective α1-adrenergic receptor antagonist.
(S)-Indacaterol V122176 (S)-Indacaterol 1235445-80-3 (S)-Indacaterol is the S-enantiomer of indacaterol.
(S)-Mabuterol V122187 (S)-Mabuterol 56707-25-6 (S)-Mabuterol is a selective β2-adrenergic receptor agonist that has shown effects of lowering blood pressure, increasing heart rate, and increasing contractility in animal models.
(S)-Trimetoquinol hydrochloride V110173 (S)-Trimetoquinol hydrochloride 18559-59-6 (S)-Trimethylquinolone hydrochloride (compound 1) is a potent, nonselective, nonclassical β-adrenergic agonist and a nonprostaglandin A2/prostaglandin H2 antagonist.
(±)-4-Hydroxy propranolol β-D-glucuronide V102882 (±)-4-Hydroxy propranolol β-D-glucuronide 94731-13-2 (±)-4-Hydroxypropranolol β-D-glucuronide is a metabolite of the β-adrenergic receptor antagonist 4-hydroxypropranolol.
(±)-Desisopropylpropranolol V121228 (±)-Desisopropylpropranolol 20862-11-7 (±)-Desisopropylpropranolol is a metabolite of propranolol.
(±)-Penbutolol V102678 (±)-Penbutolol 36507-48-9 (±)-Penbutolol ((Rac)-Penbutolol) is the racemic form of penbutolol.
(±)-WB 4101 V115621 (±)-WB 4101 613-67-2 (±)-WB 4101 is a highly selective α1-adrenergic receptor inhibitor.
2,3-MDMA hydrochloride V107164 2,3-MDMA hydrochloride 168968-01-2 2,3-MDMA hydrochloride is a norepinephrine transporter and serotonin transporter inhibitor with IC50 values of 6.2 μM and 82 μM, respectively.
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