Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V3749 | SSE15206 | 1370046-40-4 | SSE15206 is a mitotic inhibitor, specifically, a microtubule depolymerizing agent that can overcome multidrug resistance. |
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V79817 | SSE1806 | SSE1806 is an analogue of podophyllotoxin (a natural antimitotic agent) and a microtubule/tubulin inhibitor (antagonist) with significant anticancer and antiproliferation activities. | |
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V89584 | ST-401 | 2419942-78-0 | ST-401 is a microtubule targeting agent (MTA) and a brain-permeable microtubule (MT) assembly inhibitor. |
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V55252 | Sudocetaxel | 1234218-62-2 | Sudocetaxel is a microtubule depolymerization inhibitor for pH-sensitive docetaxel release. |
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V54251 | T-peptide | 2022956-62-1 | T-peptide is a Tuftsin analog that may be utilized to study human immunodeficiency virus (HIV) infection. |
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V75811 | Taccalonolide AJ | 2230777-09-8 | Taccalonolide AJ is a semi-synthetic compound with cellular microtubule stabilizing activity. |
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V76455 | Taltobulin hydrochloride (HTI-286 hydrochloride; SPA-110 hydrochloride) | Taltobulin HCl (HTI-286 HCl) is a synthetic tripeptide cysteine analogue. | |
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V31385 | Taltobulin trifluoroacetate | 228266-41-9 | Taltobulin trifluoroacetate (HTI-286; HTI286; SPA-110; SPA110), the trifluoroacetate salt of taltobulin, is an nalogue of Hemiasterlin, acting as a tubulin inhibitor and used as an ADC cytotoxin (warhead). |
|
V84139 | TAM557 | 1802499-20-2 | |
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V88696 | TAM557 TFA | TAM557 TFA is a cytotoxic tubulysin compound that has been modified for conjugation to targeting molecules such as proteins, peptides, small molecules or polymeric carriers that carry the targeting principle. | |
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V35220 | Tau tracer 1 | 2173353-53-0 | Tau tracer 1 is a Tau tracer used for imaging Tau protein aggregates. |
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V35219 | Tau tracer 2 (Pl-2620) | 2173361-80-1 | Tau tracer 2 (Pl-2620) is a Tau tracer used for imaging Tau protein aggregates. |
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V55255 | Taxinine B (Taxinin B) | 18457-44-8 | Taxinine B is a taxane extracted from the Japanese yew Taxus Cuspid. |
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V16531 | TN-16 | 33016-12-5 | TN-16 (TN16; NSC-239274) is a potent tubulin inhibitor (antitubulin/antimitotic agent) with anticancer activity. |
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V104043 | Trastuzumab MMAE | Trastuzumab MMAE is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). | |
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V88457 | Trilexium | 1983180-82-0 | Trilexium (TRX-E-009-1) is a third generation benzopyran, structurally related to TRX-E-002-1. |
|
V88700 | Tubulin degrader 1 | Tubulin degrader 1 (Compound 5i) is a BML284 derivative, an orally active colchicine-mediated non-covalent tubulin degrader with IC50 values of 0.02 - 0.05 μM against five tumor cell lines (Hela, HCT116, MCF-7, K562 and Molm-13). | |
|
V75822 | Tubulin inhibitor 15 | 2767446-36-4 | Tubulin inhibitor 15 is a potent tubulin inhibitor. |
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V75820 | Tubulin inhibitor 16 | 2767446-32-0 | Tubulin inhibitor 16 is a potent tubulin inhibitor. |
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V79473 | Tubulin inhibitor 31 | Tubulin inhibitor 31 is a potent tubulin inhibitor (antagonist) with IC50 of 4 µM. |
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