Progesterone receptor (PR) is a member of the steroid/thyroid hormone-retinoid receptor superfamily of ligand-activated nuclear transcription factors.
The development, differentiation, and maintenance of female reproductive tissue depends heavily on progesterone receptor.The ability of the progesterone receptor to bind to a wide range of ligands results in a wide range of transcriptional responses, including full agonism, full antagonism, and several mixed profiles in between. Progesterone receptors, such as progesterone, cause the PR ligand binding domain (LBD) to change its conformation, which in turn controls subsequent gene regulatory cascades.
Human PR-A and PR-B are two different types of progesterone receptors that mediate the biological response to progesterone in humans.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V67768 | Progesterone-13C3 (progesterone 13C3) | 327048-87-3 | Progesterone-13C3 is a 13C (carbon 13)-labeled progesterone. |
|
V67769 | Progesterone-13C5 (Pregn-4-ene-3,20-dione-13C5) | 2687960-32-1 | Progesterone-13C5 is a 13C (carbon 13)-labeled progesterone. |
|
V67767 | Progesterone-d9 (Pregn-4-ene-3,20-dione-d9) | 15775-74-3 | Progesterone-d9 is the deuterated form of Progesterone. |
|
V5585 | Promegestone | 34184-77-5 | Promegestone (R-5020; RU-5020; trade name Surgestone) is a progestin medication and a synthetic progestogen acting as an agonist of the progesterone receptor. |
|
V3879 | Segesterone acetate | 7759-35-5 | Segesterone acetate (formerly known as ST1435;ST-1435 or nestorone; trade name:Annovera) is an agonist of progesterone receptor used as a female-contraceptive drug. |
|
V15733 | Tanaproget (NSP989) | 304853-42-7 | Tanaproget(NSP-989) is a novel, potent and non-steroidal progesterone receptor agonist with the potentiall to be used as a female contraception. |
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