|
V74662
|
ICMT-IN-42 |
1313602-67-3 |
ICMT-IN-42 (compound 21) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.054 μM). |
|
V74697
|
ICMT-IN-43 |
1313602-68-4 |
ICMT-IN-43 (compound 22) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.04 μM). |
|
V74685
|
ICMT-IN-44 |
1313602-69-5 |
ICMT-IN-44 (compound 23) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.167 μM). |
|
V74667
|
ICMT-IN-45 |
1313602-70-8 |
ICMT-IN-45 (compound 24) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.132 μM). |
|
V74684
|
ICMT-IN-46 |
1313602-71-9 |
ICMT-IN-46 (compound 25) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.556 μM). |
|
V74654
|
ICMT-IN-47 |
1313602-72-0 |
ICMT-IN-47 (compound 26) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.76 μM). |
|
V74656
|
ICMT-IN-48 |
337486-54-1 |
ICMT-IN-48 (compound 1) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor that is competitive (Km=13 μM) for the prenylated methyl acceptor, the first substrate of ICMT. |
|
V74663
|
ICMT-IN-49 |
303728-92-9 |
ICMT-IN-49 (compound 2) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.12 μM). |
|
V74698
|
ICMT-IN-5 |
1313602-92-4 |
ICMT-IN-5 (compound 46) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.3 μM). |
|
V74680
|
ICMT-IN-50 |
371940-21-5 |
ICMT-IN-50 (compound 3) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.31 μM). |
|
V74694
|
ICMT-IN-51 |
1313602-89-9 |
ICMT-IN-51 (compound 43) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.55 μM). |
|
V74693
|
ICMT-IN-52 |
1313602-90-2 |
ICMT-IN-52 (compound 44) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.052 μM). |
|
V74668
|
ICMT-IN-53 |
1443253-17-5 |
ICMT-IN-53 (compound 12) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.96 μM) with PAMPA permeability and antiproliferation activity. |
|
V74692
|
ICMT-IN-54 |
908856-14-4 |
ICMT-IN-54 (compound 7c) is an adamantyl analogue and an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=12.4 μM) that can inhibit ICMT methylation. |
|
V74695
|
ICMT-IN-55 |
1313602-77-5 |
ICMT-IN-55 (compound 31) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (antagonist) with IC50=90 nM. |
|
V74682
|
ICMT-IN-6 |
1313602-75-3 |
ICMT-IN-6 (compound 29) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.09 μM). |
|
V74657
|
ICMT-IN-7 |
1313603-21-2 |
ICMT-IN-7 (compound 74) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.015 μM). |
|
V74658
|
ICMT-IN-8 |
1313602-76-4 |
ICMT-IN-8 (compound 30) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.652 μM). |
|
V74669
|
ICMT-IN-9 |
1313602-93-5 |
ICMT-IN-9 (compound 47) is an isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitor (IC50=0.16 μM). |
|
V74696
|
J1-1 |
1244769-10-5 |
J1-1 is an inhibitor (blocker/antagonist) of ICMT with IC50 of 1.0 μM and has anti-cancer effect. |