| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V112071 | 2,4-Dinitrobenzenesulfonic acid | 89-02-1 | 2,4-Dinitrobenzenesulfonic acid (compound 3) is an extracellular 5'-nucleotidase (CD73) inhibitor with a Ki value of 63 μM for humans and 144 μM for rats. |
|
V127765 | 8-BuS-AMP | 344402-39-7 | 8-BuS-AMP is an NTPDase1 inhibitor and a CD73/CD39 inhibitor. Its IC50 value for human NTPDase1 is 35 μM, and its Ki value is 0.292 μM. Its Ki values for human CD73 and CD39 are 1.19 μM and 0.847 μM, respectively. |
|
V128013 | AB-680 ammonium | AB-680 ammonium is a highly effective, reversible, and selective inhibitor of CD73 (an exonuclease), with a Ki value of 4.9 pM for hCD73 and a selectivity of over 10,000-fold for the related exonuclease CD39. | |
|
V106384 | Ansipastobart | Ansipastobart is a human IgG1λ2 antibody directed against NT5E. | |
|
V129924 | BC-010 | BC-010 is a human monoclonal antibody (mAb) that targets NT5E/CD73. | |
|
V51270 | BK-50164 | 2204291-78-9 | BK50164 is a potent CD73 with IC50 of 13.089 µM. |
|
V130408 | BMS-986179 | BMS-986179 is a human monoclonal antibody (mAb) that targets NT5E/CD73. | |
|
V74772 | CD73-IN-12 | 2773502-79-5 | CD73-IN-12 is a potent inhibitor of CD73, which is linked to tumor growth, angiogenesis, and metastasis. |
|
V74771 | CD73-IN-13 | 2773423-69-9 | CD73-IN-13 is a potent inhibitor of CD73, which is linked to tumor growth, angiogenesis, and metastasis. |
|
V51264 | CD73-IN-14 | 2407356-67-4 | CD73-IN-14 is a specific, and orally bioactive CD73-fold with IC50 of 0.17 nM. |
|
V86825 | CD73-IN-15 | CD73-IN-15 (compound 12f) is a potent inhibitor of CD73 with IC50 of 60 nM. | |
|
V96828 | CD73-IN-16 | CD73-IN-16 (Compound 18) is an inhibitor of hCD73 with IC50 of 0.28 μM. | |
|
V97140 | CD73-IN-17 | CD73-IN-17 (Compound 19) is a CD73 inhibitor with IC50 of 0.1 μM for hCD73. | |
|
V94826 | CD73-IN-18 | 3037968-61-6 | CD73-IN-18 (Compound 35j) is an orally available inhibitor of extracellular 5-nucleotidase (CD73). |
|
V105112 | CD73-IN-19 | 333329-22-9 | CD73-IN-19 (compound 4ab) is a CD73 inhibitor (inhibits CD73 enzymatic activity by 44% at 100 μM). |
|
V74773 | CD73-IN-2 | 2452209-05-9 | CD73-IN-2 is a potent CD73 inhibitor (antagonist) with IC50 of 0.09 nM. |
|
V120280 | CD73-IN-20 | CD73-IN-20 (compound 5c) is an e5′NT (CD73) inhibitor (IC50: 0.37 μM). | |
|
V131225 | CD73-IN-21 | CD73-IN-21 is an extracellular 5′-nucleotidase (CD73) inhibitor with Ki values of 20 nM for human CD73 and 302 nM for mouse CD73. | |
|
V131226 | CD73-IN-22 | CD73-IN-22 is a non-nucleoside CD73 inhibitor with an IC50 value of 0.07 μM. | |
|
V51265 | CD73-IN-4 | 2216764-29-1 | CD73-IN-4 is a selective, highly effective methylene phosphate CD73 with IC50 of 2.6 nM for human CD73. |