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Structure Cat No. Product Name CAS No. Product Description
IDO1-IN-16 V49323 IDO1-IN-16 2677054-63-4 IDO1-IN-16 is a novel IDO1 inhibitor with immunomodulating and anticancer activity.
IDO1-IN-17 V49298 IDO1-IN-17 2677054-58-7 IDO1-IN-17 is a novel IDO1 inhibitor with immunomodulating and anticancer activity.
IDO1-IN-18 V46980 IDO1-IN-18 2328099-08-5 IDO1-IN-18 (Compound 14) is a potent IDO1 inhibitor.
IDO1-IN-19 V47095 IDO1-IN-19 2328099-11-0 IDO1-IN-19 (Compound 17) is a potent IDO1 inhibitor.
IDO1-IN-20 V47389 IDO1-IN-20 2415246-15-8 IDO1-IN-20 is a novel and potent inhibitor ofIndoleamine 2,3-dioxygenase 1 (IDO1), which is the enzyme catalyzing the oxidative metabolism of tryptophan, which accounts for cancer immunosuppression in tumor microenvironment.
IDO1/2-IN-1盐酸 V47082 IDO1/2-IN-1 HCl 2310286-60-1 IDO1/2-IN-1 HCl is a dual IDO1/IDO2 inhibitorwith anticancer activity.
IDO1/TDO-IN-1 V49387 IDO1/TDO-IN-1 2379527-72-5 IDO1/TDO-IN-1 is a dual IDO1 and TDO inhibitor with anticancer activity.
IDO1/TDO-IN-2 V46934 IDO1/TDO-IN-2 5466-47-7 IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC50 s of 0.1 and 0.07 μM.
IDO1/TDO-IN-3 V47032 IDO1/TDO-IN-3 2347579-03-5 IDO1/TDO-IN-3 isa novel dual inhibitor of IDO1/TDO with anticancer activity.
IDO1/TDO-IN-4 V43646 IDO1/TDO-IN-4 461424-21-5 IDO1/TDO-IN-4 is a novel dual IDO1/TDOinhibitor, with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO).
IDO2-IN-1 V43465 IDO2-IN-1 2803768-09-2 IDO2-IN-1 is a novel and orally bioactiveIndoleamine 2,3-dioxygenase 2(IDO2) inhibitor with the potential to be used for inflammatory and autoimmune diseases.
IEM-1460 V48923 IEM-1460 121034-89-7 IEM-1460 blocks AMPA and NMDA glutamate receptors and has anticonvulsant (antiepileptic/antiseizure) effects in vivo.
Ifebemtinib (BI853520; IN10018) HCl V43395 Ifebemtinib (BI-853520; IN-10018) HCl 1227948-82-4 BI-853520 HCl (IN10018 hydrochloride)isnovel, potent and highly selective focal adhesion kinase (FAK) inhibitor (recombinant FAK IC50=1 nM) andPTK2 kinase inhibitor withanti-tumor activity.
IHCH-3064 V41569 IHCH-3064 2420562-65-6 IHCH-3064 is an A2AR and HDAC dual-target immunotherapeutic agent.
IHCH-3064 HCl V50637 IHCH-3064 HCl IHCH-3064 HCl is an A2AR and HDAC dual-target immunotherapeutic agent.
IHMT-EZH2-115 V41557 IHMT-EZH2-115 IHMT-EZH2-115 is a novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor with the potential for treating B-Cell Lymphomas.
IHMT-MST1-58 V42242 IHMT-MST1-58 2414484-25-4 IHMT-MST1-58 is a potent and specific STE20-like protein 1 kinase (MST1) inhibitor (antagonist) with oral activity and IC50 of 23 nM.
IHMT-TRK-284 V48674 IHMT-TRK-284 2416844-79-4 IHMT-TRK-284 (Compound 34) is a potent, orally bioactive type II TRK kinase inhibitor (antagonist) with IC50s of 10.5, 0.7 and 2.6 nM for TRKA, B and C respectively.
IKKβ-IN-1 V49614 IKKβ-IN-1 2410423-31-1 IKKβ-IN-1 is a novel and orally bioavailable IkappaB (IKK-β) inhibitor (IC50 = 0.20 μM) with anti-inflammatory activity.
IL-17 modulator 6 V50142 IL-17 modulator 6 2725869-16-7 IL-17 modulator 6 (compound 61) is a potent interleukin 17 (IL-17) modulator (pIC50=9.1).
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