Structure | Cat No. | Product Name | CAS No. | Product Description |
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V49323 | IDO1-IN-16 | 2677054-63-4 | IDO1-IN-16 is a novel IDO1 inhibitor with immunomodulating and anticancer activity. |
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V49298 | IDO1-IN-17 | 2677054-58-7 | IDO1-IN-17 is a novel IDO1 inhibitor with immunomodulating and anticancer activity. |
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V46980 | IDO1-IN-18 | 2328099-08-5 | IDO1-IN-18 (Compound 14) is a potent IDO1 inhibitor. |
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V47095 | IDO1-IN-19 | 2328099-11-0 | IDO1-IN-19 (Compound 17) is a potent IDO1 inhibitor. |
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V47389 | IDO1-IN-20 | 2415246-15-8 | IDO1-IN-20 is a novel and potent inhibitor ofIndoleamine 2,3-dioxygenase 1 (IDO1), which is the enzyme catalyzing the oxidative metabolism of tryptophan, which accounts for cancer immunosuppression in tumor microenvironment. |
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V47082 | IDO1/2-IN-1 HCl | 2310286-60-1 | IDO1/2-IN-1 HCl is a dual IDO1/IDO2 inhibitorwith anticancer activity. |
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V49387 | IDO1/TDO-IN-1 | 2379527-72-5 | IDO1/TDO-IN-1 is a dual IDO1 and TDO inhibitor with anticancer activity. |
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V46934 | IDO1/TDO-IN-2 | 5466-47-7 | IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC50 s of 0.1 and 0.07 μM. |
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V47032 | IDO1/TDO-IN-3 | 2347579-03-5 | IDO1/TDO-IN-3 isa novel dual inhibitor of IDO1/TDO with anticancer activity. |
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V43646 | IDO1/TDO-IN-4 | 461424-21-5 | IDO1/TDO-IN-4 is a novel dual IDO1/TDOinhibitor, with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO). |
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V43465 | IDO2-IN-1 | 2803768-09-2 | IDO2-IN-1 is a novel and orally bioactiveIndoleamine 2,3-dioxygenase 2(IDO2) inhibitor with the potential to be used for inflammatory and autoimmune diseases. |
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V48923 | IEM-1460 | 121034-89-7 | IEM-1460 blocks AMPA and NMDA glutamate receptors and has anticonvulsant (antiepileptic/antiseizure) effects in vivo. |
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V43395 | Ifebemtinib (BI-853520; IN-10018) HCl | 1227948-82-4 | BI-853520 HCl (IN10018 hydrochloride)isnovel, potent and highly selective focal adhesion kinase (FAK) inhibitor (recombinant FAK IC50=1 nM) andPTK2 kinase inhibitor withanti-tumor activity. |
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V41569 | IHCH-3064 | 2420562-65-6 | IHCH-3064 is an A2AR and HDAC dual-target immunotherapeutic agent. |
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V50637 | IHCH-3064 HCl | IHCH-3064 HCl is an A2AR and HDAC dual-target immunotherapeutic agent. | |
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V41557 | IHMT-EZH2-115 | IHMT-EZH2-115 is a novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor with the potential for treating B-Cell Lymphomas. | |
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V42242 | IHMT-MST1-58 | 2414484-25-4 | IHMT-MST1-58 is a potent and specific STE20-like protein 1 kinase (MST1) inhibitor (antagonist) with oral activity and IC50 of 23 nM. |
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V48674 | IHMT-TRK-284 | 2416844-79-4 | IHMT-TRK-284 (Compound 34) is a potent, orally bioactive type II TRK kinase inhibitor (antagonist) with IC50s of 10.5, 0.7 and 2.6 nM for TRKA, B and C respectively. |
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V49614 | IKKβ-IN-1 | 2410423-31-1 | IKKβ-IN-1 is a novel and orally bioavailable IkappaB (IKK-β) inhibitor (IC50 = 0.20 μM) with anti-inflammatory activity. |
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V50142 | IL-17 modulator 6 | 2725869-16-7 | IL-17 modulator 6 (compound 61) is a potent interleukin 17 (IL-17) modulator (pIC50=9.1). |