|
V50422
|
(E/Z)-Zotiraciclib citrate-TG-02 citrate; SB-1317 citrate |
1204918-73-9 |
(E/Z)-Zotiraciclib citrate (TG02 citrate; SB1317 citrate is a novel and potent CDK2, JAK2, and FLT3 inhibitorwith the potential for the treatment of cancer. |
|
V37604
|
(R)-Apremilast ((R)-CC10004) |
608141-44-2 |
R)-Apremilast ((R)-CC-10004) is the R-isomer of Apremilast (also known as CC-10004), which is a thalidomide analog and is a novel and orally bioavailable small molecule inhibitor of the phosphodiesterase 4 (PDE4) with potential anti-inflammatory activity. |
|
V44664
|
(±)-Levomepromazine (Methotrimeprazine) |
851-68-3 |
(±)-Levomepromazine is the racemate of Levomepromazine. |
|
V41444
|
ARV-471 |
2229711-08-2 |
ARV-471 (ARV471)is a first-in-class, selective and orally bioavailable PROTAC-based Estrogen Receptor (AR) degrader. |
|
V41400
|
Bay-3827 |
2377576-35-5 |
BAY-3827 is a potent and specific AMPK inhibitor (antagonist) with IC50s of 1.4 nM (10 µM ATP) and 15 nM (2 mM ATP). |
|
V37626
|
Benzimidazole |
51-17-2 |
Benzimidazole is a heterocyclic compound commonly and widely used for the synthesis of many bioactive molecules with various biological activities such as anti-cancer, anti-viral, anti-bacterial, anti-fungal, anti-helmintic, anti-inflammatory, proton pump inhibitor and anti-coagulant property. |
|
V41447
|
BIIB068 |
1798787-27-5 |
BIIB068 (BIIB-068) is a novelreversible and orally bioavailable BTK inhibitor with the potential to be used for autoimmune diseases such as systemic lupus erythematosus (SLE). |
|
V37648
|
BMVC-8C3O |
1301708-12-2 |
BMVC-8C3O is a novel ligand of DNA G-quadruplexe (G4) that can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s. |
|
V41389
|
C-021 (CCR4 antagonist) |
864289-85-0 |
C021 (C-021; CCR4 antagonist) is a novel and potent CCR4 antagonist with anti-inflammatory activity. |
|
V44274
|
Capmatinib HCl |
1029714-89-3 |
Capmatinib (INC280; INCB28060) HCl is a potent, orally bioactive, selective, ATP-competitive c-Met kinase inhibitor (IC50=0.13 nM). |
|
V42163
|
CCR6 antagonist 1 |
588674-64-0 |
CCR6 antagonist 1 is a CCR6 antagonist with the potential tobe used in autoimmune diseases, e. |
|
V43698
|
Cefpodoxime |
80210-62-4 |
Cefpodoxime (R-3763; U-76253A) is a broad spectrumantibacterial agent that acts bybinding to penicillin binding proteins (PBPs), thus inhibiting peptidoglycan synthesis, leading to disruption ofbacterialcell wall biosynthesis. |
|
V41588
|
Compound 6q |
|
Compound 6q is a novel and potent steroidal anti-inflammatory agent that has the potential to be used in the treatment of IBD (inflammatory bowel diseases). |
|
V49209
|
DDO-7263 |
2254004-96-9 |
DDO-7263 is a 1,2,4-Oxadiazole analogue and a potent Nrf2-ARE activator. |
|
V44747
|
Fast Red Violet LB |
32348-81-5 |
Fast Red Violet LB is a dye that can be used for staining TRAP (tartrate resistantacid phosphatase). |
|
V49031
|
Fluridone |
59756-60-4 |
Fluridone isan herbicide acting asan inhibitor of abscisic acid (ABA) biosynthesis. |
|
V41419
|
gamma-Glu-Cys |
636-58-8 |
Gamma-glutamylcysteine (amma-Glu-Cys) is a substrate for biosynthesis of L-glutathione by glutathione synthetase. |
|
V50576
|
GRK6-IN-1 |
2677786-61-5 |
GRK6-IN-1 (compound 18) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) with IC50 of 120 nM. |
|
V37640
|
GS-441524 HCl |
2378280-82-9 |
GS-441524 is an active metabolite of Remdesivir (GS-5734;Veklury) which is an FDA approved drug for treating the2019-nCoV (COVID-19 pandemic, CoronaVirus)infections. |
|
V41621
|
Hyocholic Acid |
547-75-1 |
Hyocholic Acid (3α,6α,7α-trihydroxy-5β-cholan-24-oic acid) is a biliary acid found mainlyin pig as well as in human urineat low concentrations, in particular,in urine samples from patients with cholestasis. |