PPAR

PPAR

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptor superfamily ligand-activated transcription factors that include the following three subtypes: PPAR, PPAR, and PPAR/. Higher organisms' cellular differentiation, development, metabolism (carbohydrate, lipid, and protein), as well as tumorigenesis, are all crucially regulated by PPARs. All PPARs bind to particular regions of the target genes' DNA through heterodimerization with the retinoid X receptor (RXR). Triglyceride levels are reduced and energy homeostasis is regulated when PPAR- is activated. PPAR- activation improves the metabolism of glucose, whereas PPAR-/ activation improves the metabolism of fatty acids.

PPAR related products

Structure Cat No. Product Name CAS No. Product Description
V2726 Troglitazone 97322-87-7 Troglitazone (formerly known as CI991) is a novel potent PPARγ agonist with anti-inflammatory and anti-tumor activity.
V0829 WY-14643 (Pirinixic Acid) 50892-23-4 Pirinixic Acid (also known as NSC 310038; NSC310038;WY-14643; WY 14643) is a novel, highly potent and selective peroxisome proliferator and activator of PPARα with important biological activity.
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