The serine hydrolase family of enzymes includes the membrane-bound protein FAAH (Fatty Acid Amide Hydrolase).Numerous significant endogenous fatty acid amides, such as the putative anti-inflammatory compound palmitoylethanolamide (PEA) and the endogenous cannabimimetic anandamide (AEA), which induces sleep, are hydrolyzed by FAAH. A class of bioactive lipids known as fatty acid amides (FAAs) signaling is terminated by FAAH both in peripheral tissues and the central nervous system (CNS).
FAAH belongs to the amidase signature (AS) superfamily and is widely distributed in multicellular eukaryotes. FAAH has a key role in the control of the cannabinoid signaling, through the hydrolysis of the endocannabinoids anandamide and in some tissues 2-arachidonoylglycerol.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0907 | URB597 | 546141-08-6 | URB597 (also known as KDS4103,URB-597; KDS-4103) is a novel, potent, selective,orally bioavailable fatty acid amide hydrolase (FAAH) inhibitor with antidepressant and analgesic activity. |
|
V2207 | URB937 | 1357160-72-5 | Desrciption: URB-937 is a potent and novel FAAH inhibitor and increases anandamide levels, with an IC50 of 26.8 nM. |
|
V2303 | WWL-154 | 1338574-93-8 | WWL154 is an analog of JZL184 and a FAAH-4 inhibitor. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
