MMP

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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MMP

MMPs (Matrix metalloproteinases) are zinc-dependent endopeptidases.The metzincin superfamily of proteases, to which the MMPs belong, is a larger group of enzymes. MMPs can process a variety of bioactive molecules in addition to breaking down various extracellular matrix proteins. They have been linked to the inactivation of chemokines and cytokines as well as the cleavage of cell surface receptors and the release of apoptotic ligands.Additionally, it is believed that MMPs have a significant impact on the proliferation, migration, differentiation, angiogenesis, apoptosis, and host defense of cells. It is believed that MMP-2 and MMP-9 are crucial for metastasis. MMP-1 is regarded as being significant in osteoarthritis and rheumatoid arthritis. Recent research indicates that MMPs are actively involved in the pathogenesis of aortic aneurysms. The structural proteins of the aortic wall are degraded by excess MMPs. Acute and chronic cardiovascular diseases both exhibit dysregulation of the balance between MMPs and TIMPs.

MMP related products

Cat No.	Product Name	CAS No.	Product Description
V87620	Highly purified Type III collagen, from bovine skin		Highly purified Type III collagen, from bovine skin (Bovine Type III collagen, immunization grade) is an immune grade collagen derived from bovine skin, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V87613	Highly purified Type III collagen, from human placenta		Highly purified Type III collagen, from human placenta (Human Type III collagen, immunization grade) is an immune grade collagen derived from human placenta, which can stimulate the immune system of animals to produce specific antibodies against this collagen.
V101390	Highly purified Type III collagen, from porcine skin		Highly purified Porcine Skin Type III Collagen (Porcine Skin Type III Collagen, Immune Grade) is immune grade collagen extracted from pig skin, which can stimulate the animal immune system to produce specific antibodies against collagen.
V101396	Highly purified Type IX collagen, from bovine articular cartilage		Highly purified bovine articular cartilage type IX collagen (bovine type IX collagen, immune grade) is immune grade collagen extracted from bovine articular cartilage, which can stimulate the animal immune system to produce specific antibodies against collagen.
V87624	Highly purified Type IX collagen, from chick articular cartilage		Highly purified Type IX collagen, from chick articular cartilage (Chick Type IX collagen, immunization grade) is an immune grade collagen derived from chicken articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V101402	Highly purified Type IX collagen, from porcine articular cartilage		Highly purified porcine articular cartilage type IX collagen (porcine type IX collagen, immune grade) is an immune grade collagen extracted from porcine articular cartilage, which can stimulate the animal immune system to produce specific antibodies against this collagen.
V87621	Highly purified Type V collagen, from bovine amnion		Highly purified Type V collagen, from bovine amnion (Bovine Amnion Type V collagen, immunization grade) is an immune grade collagen derived from bovine amnion, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V101392	Highly purified Type V collagen, from human amnion		Highly purified type V collagen from human amniotic membrane (human amniotic membrane type V collagen, immune grade) is an immune grade collagen extracted from human amniotic membrane that can stimulate the animal immune system to produce specific antibodies against collagen.
V101389	Highly purified Type V collagen, from human placenta		Highly purified Type V collagen from human placenta (Human Placental Type V Collagen, Immune Grade) is an immune grade collagen extracted from the human placenta that can stimulate the animal immune system to produce specific antibodies against this collagen.
V87625	Highly purified Type V collagen, from mouse intestine		Highly purified Type V collagen, from mouse intestine (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse intestine, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V101394	Highly purified Type XI collagen, from bovine articular cartilage		Highly purified Type XI collagen from bovine articular cartilage (Bovine Type XI collagen, immune grade) is immune grade collagen extracted from bovine articular cartilage, which can stimulate the animal immune system to produce specific antibodies against collagen.
V87623	Highly purified Type XI collagen, from chick articular cartilage		Highly purified Type XI collagen, from chick articular cartilage (Chick Type XI collagen, immunization grade) is an immune grade collagen derived from chicken articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V87617	Highly purified Type XI collagen, from human sternal cartilage		Highly purified Type XI collagen, from human sternal cartilage (Human Type XI collagen, immunization grade) is an immune grade collagen derived from human sternal cartilage, which can stimulate the immune system of animals to produce specific antibodies against this collagen.
V87626	Highly purified Type XI collagen, from porcine articular cartilage		Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V76931	Histatin 5 TFA (Histatin 5 Trifluoroacetate)		Histatin 5 TFA inhibits host matrix metalloproteinases MMP-2 and MMP-9 activities with IC50s of 0.57 and 0.25 μM, respectively.
V73261	Isozedoarondiol	108887-68-9	Isozedoarondiol is extracted from the rhizome of Turmeric.
V31028	Luteolin 7-O-glucuronide	29741-10-4	Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
V73252	Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2	158584-08-8	Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 is a biologically active peptide.
V73219	Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2	720710-69-0	Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide and a quenched MMP peptide substrate that may be utilized to quantify MMP enzymatic activity in real time .
V77797	Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2		Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a biologically active peptide.