MMP

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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MMP

MMPs (Matrix metalloproteinases) are zinc-dependent endopeptidases.The metzincin superfamily of proteases, to which the MMPs belong, is a larger group of enzymes. MMPs can process a variety of bioactive molecules in addition to breaking down various extracellular matrix proteins. They have been linked to the inactivation of chemokines and cytokines as well as the cleavage of cell surface receptors and the release of apoptotic ligands.Additionally, it is believed that MMPs have a significant impact on the proliferation, migration, differentiation, angiogenesis, apoptosis, and host defense of cells. It is believed that MMP-2 and MMP-9 are crucial for metastasis. MMP-1 is regarded as being significant in osteoarthritis and rheumatoid arthritis. Recent research indicates that MMPs are actively involved in the pathogenesis of aortic aneurysms. The structural proteins of the aortic wall are degraded by excess MMPs. Acute and chronic cardiovascular diseases both exhibit dysregulation of the balance between MMPs and TIMPs.

MMP related products

Cat No.	Product Name	CAS No.	Product Description
V133134	CZh226	2196199-00-3	CZh226 is a selective PAK4 inhibitor with an IC50 of 0.0111 μM and a Ki of 0.009 μM.
V79188	Dnp-PLGLWA-DArg-NH2 TFA		Dnp-PLGLWA-DArg-NH2 TFA is a fluorescent substrate for MMP-1 and MMP-9.
V73258	Dnp-PYAYWMR	135662-06-5	Dnp-PYAYWMR is a bioactive peptide substrate that selectively targets MMP3.
V134799	E09241	1043110-13-9	E09241 is an orally effective osteoclastogenetic inhibitor.
V110569	Edaravone sulfate-d5		Edaravone sulfate-d5 is deuterated edaravone sulfate.
V73237	FFAGLDD	2703745-70-2	FFAGLDD is an MMP9-selective cleavage peptide for cytosolic delivery of doxorubicin (DOX) and achieves temporally and spatially controlled slow drug delivery and release.
V79409	FFAGLDD TFA		FFAGLDD TFA is an MMP9-selective cleavage peptide for cytosolic delivery of doxorubicin (DOX) and achieves temporally and spatially controlled slow drug delivery and release.
V77004	FN-439 TFA		FN-439 TFA is a selective collagenase-1 inhibitor.
V2835	FT 011	1001288-58-9	FT011 is a novel potent anti-inflammatory and anti-fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy.
V136553	GCRRGPLGLSLGKRRCG		GCRRGPLGLSLGKRRCG is an MMP13-specific substrate peptide that can be cleaved by MMP13.
V117054	GI-129471	130370-59-1	GI-129471 is an MMP inhibitor.
V4081	GI254023X	260264-93-5	GI254023X (also known as GI4023 and SRI028594) is a novel and potent inhibitor of MMP9 (Matrix Metallopeptidase 9)andADAM10 (A Disintegrin and Metalloproteinase 10) withIC50s of 2.5 and 5.3 nM, respectively.
V102695	GM1489	171347-75-4	GM1489 is a MMP inhibitor that inhibits MMP activity and reduces degradation at the resin-dentin interface, thereby enhancing bond stability.
V136860	GPLGIAGQC	1423719-70-3	GPLGIAGQC is a peptide that can be cleaved by MMP2.
V106188	GPLGLAGGWGERDGS	1449337-90-9	GPLGLAGGWGERDGS is a peptide with MMP enzyme-responsiveness and tumor-targeting functions that can be used to monitor enzyme-guided nanoparticle assembly in tumors.
V136861	GPLGVRG	915404-04-5	GPLGVRG is an MMP13-responsive linker peptide.
V136862	GPLGVRGC	1257658-47-1	GPLGVRGC is a cysteine-tagged variant of GPLGVRG.
V2172	GW280264X	866924-39-2	GW280264X is an ADAM10/TACE (ADAM17) metalloproteinase inhibitor.
V87612	Highly purified Type I collagen, from canine skin		Highly purified Type I collagen, from canine skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from canine skin, which can stimulate the animal's immune system to produce specific antibodies against the collagen.
V137367	Highly purified Type I collagen, from chick skin		Highly purified Type I collagen from chicken skin is an immune-grade collagen derived from chicken skin that can stimulate the animal's immune system to produce specific antibodies against this collagen.