Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V73432 | mPEG-CHO (MW 2000) (mPEG-Aldehyde (MW 2000)) | 70086-22-9 | mPEG-CHO (MW 2000) participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. |
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V87562 | mPEG-Cholesterol,MW 2000 | mPEG-Cholesterol, MW 2000 is a PEGylated lipid that self-assembles into micelle-like structures in water. | |
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V74060 | mPEG-DSPE (MW 2000) (Methoxy-poly(ethylene glycol)-distaroylphosphatidylethanolamine (MW 2000)) | 147867-65-0 | mPEG-DSPE (MW 2000) is a phospholipid-polyethylene glycol conjugate with both hydrophilic and hydrophobic properties. |
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V93309 | mPEG2000-CLS | mPEG2000-CLS (mPEG2000-cholesterol) is a PEGylated form of cholesterol. | |
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V87556 | MPEG2000-DMG | MPEG2000-DMG is a synthetic lipid composed of polyethylene glycol and dimyristoyl glycerol, which is used to prepare lipid nanoparticles (LNPs). | |
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V90404 | MR-2-93-3 | 2941228-90-4 | MR-2-93-3 is a long-chain fatty acid that can be used to deliver polynucleotides. |
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V74069 | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analog of TT3. |
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V96799 | NH2-GG-DSPE | 1364335-16-9 | NH2-GG-DSPE is a lipid compound that can be used to prepare liposomes. |
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V74070 | NT1-014B | 2739805-64-0 | NT1-014B is a potent NT1-lipid encapsulating amphotericin B (AmB). |
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V90407 | Octadecanedioic acid mono-L-carnitine ester | 123233-50-1 | Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid that can be used to synthesize lipid nanoparticles (LNPs). |
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V73456 | OF-Deg-Lin | 1853202-95-5 | OF-Deg-Lin is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
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V90402 | OH-C-Chol | 496801-51-5 | OH-C-Chol is a cationic liposome that can be used as a siRNA delivery vehicle. |
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V83449 | OH-Chol | 191173-82-7 | |
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V104364 | PEG(2000)-C-DMG | 1443687-74-8 | PEG(2000)-C-DMG is a PEGylated derivative of 1,2-dimyristoyl-sn-glycerol that can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA. |
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V73478 | PEG-bis-amine (MW 1000) (Poly(ethylene glycol)-bis-amine (MW 1000)) | 24991-53-5 | PEG-bis-amine (MW 1000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin. |
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V73416 | PEG-bis-amine (MW 8000) (Poly(ethylene glycol)-bis-amine (MW 8000)) | 24991-53-5 | PEG-bis-amine (MW 8000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin. |
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V76648 | PEG2000-C-DMG | PEG2000-C-DMG, a PEGylated lipid, may be utilized to prepare Onpattro. | |
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V81065 | PEG2000-DGG | PEG2000-DGG is a synthetic lipid. | |
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V74055 | PEG2000-DSPE | 247925-28-6 | PEG2000-DSPE may be utilized to prepare stable nucleic acid lipid particles (SNALPs). |
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V84109 | Phosphatidylcholines, egg | 97281-44-2 |