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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
mPEG-CHO (MW 2000) (mPEG-Aldehyde (MW 2000)) V73432 mPEG-CHO (MW 2000) (mPEG-Aldehyde (MW 2000)) 70086-22-9 mPEG-CHO (MW 2000) participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle.
mPEG-Cholesterol,MW 2000 V87562 mPEG-Cholesterol,MW 2000 mPEG-Cholesterol, MW 2000 is a PEGylated lipid that self-assembles into micelle-like structures in water.
mPEG-DSPE (MW 2000) (Methoxy-poly(ethylene glycol)-distaroylphosphatidylethanolamine (MW 2000)) V74060 mPEG-DSPE (MW 2000) (Methoxy-poly(ethylene glycol)-distaroylphosphatidylethanolamine (MW 2000)) 147867-65-0 mPEG-DSPE (MW 2000) is a phospholipid-polyethylene glycol conjugate with both hydrophilic and hydrophobic properties.
mPEG2000-CLS V93309 mPEG2000-CLS mPEG2000-CLS (mPEG2000-cholesterol) is a PEGylated form of cholesterol.
MPEG2000-DMG V87556 MPEG2000-DMG MPEG2000-DMG is a synthetic lipid composed of polyethylene glycol and dimyristoyl glycerol, which is used to prepare lipid nanoparticles (LNPs).
MR-2-93-3 V90404 MR-2-93-3 2941228-90-4 MR-2-93-3 is a long-chain fatty acid that can be used to deliver polynucleotides.
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide V74069 N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide 2922283-38-1 N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analog of TT3.
NH2-GG-DSPE V96799 NH2-GG-DSPE 1364335-16-9 NH2-GG-DSPE is a lipid compound that can be used to prepare liposomes.
NT1-014B V74070 NT1-014B 2739805-64-0 NT1-014B is a potent NT1-lipid encapsulating amphotericin B (AmB).
Octadecanedioic acid mono-L-carnitine ester V90407 Octadecanedioic acid mono-L-carnitine ester 123233-50-1 Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid that can be used to synthesize lipid nanoparticles (LNPs).
OF-Deg-Lin V73456 OF-Deg-Lin 1853202-95-5 OF-Deg-Lin is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles.
OH-C-Chol V90402 OH-C-Chol 496801-51-5 OH-C-Chol is a cationic liposome that can be used as a siRNA delivery vehicle.
OH-Chol V83449 OH-Chol 191173-82-7
PEG(2000)-C-DMG V104364 PEG(2000)-C-DMG 1443687-74-8 PEG(2000)-C-DMG is a PEGylated derivative of 1,2-dimyristoyl-sn-glycerol that can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA.
PEG-bis-amine (MW 1000) (Poly(ethylene glycol)-bis-amine (MW 1000)) V73478 PEG-bis-amine (MW 1000) (Poly(ethylene glycol)-bis-amine (MW 1000)) 24991-53-5 PEG-bis-amine (MW 1000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin.
PEG-bis-amine (MW 8000) (Poly(ethylene glycol)-bis-amine (MW 8000)) V73416 PEG-bis-amine (MW 8000) (Poly(ethylene glycol)-bis-amine (MW 8000)) 24991-53-5 PEG-bis-amine (MW 8000) synthesizes folic acid-conjugated polymer micelles for encapsulation of the anticancer agent 9-nitrocamptothecin.
PEG2000-C-DMG V76648 PEG2000-C-DMG PEG2000-C-DMG, a PEGylated lipid, may be utilized to prepare Onpattro.
PEG2000-DGG V81065 PEG2000-DGG PEG2000-DGG is a synthetic lipid.
PEG2000-DSPE V74055 PEG2000-DSPE 247925-28-6 PEG2000-DSPE may be utilized to prepare stable nucleic acid lipid particles (SNALPs).
Phosphatidylcholines, egg V84109 Phosphatidylcholines, egg 97281-44-2
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