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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
Gal-C4-Chol V73433 Gal-C4-Chol 219850-70-1 Gal-C4-Chol is a glycosylated cholesterol analogue.
Genevant CL1 monohydrochloride V79572 Genevant CL1 monohydrochloride Genevant CL1 mono HCl is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery.
GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) V76978 GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) GL67 (N4-Spermine cholesteryl carbamate) (penta HCl) is a cationic lipid.
Glucosamine Cholesterol V90138 Glucosamine Cholesterol 1257309-90-2 Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate that can be used to prepare lipid nanoparticles (LNPs).
HAPC-Chol V87546 HAPC-Chol 1027801-73-5 HAPC-Chol is a cationic cholesterol that can be used as a component of liposome complexes.
HAPC-Chol hydroiodide V93283 HAPC-Chol hydroiodide HAPC-Chol is a cationic cholesterol that can be used as a component of liposome complexes.
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate V73419 Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate 2714482-26-3 Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate may be utilized in liposome delivery systems for the delivery of mRNA vaccines.
IAJD249 V98336 IAJD249 IAJD249 is an ionizable lipid.
IAJD93 V98223 IAJD93 IAJD93 is an ionizable lipid.
IM21.7c V93307 IM21.7c 2416939-42-7 IM21.7c is a cationic lipid that can be used to synthesize lipid nanoparticles (LNPs) for the delivery of mRNA and other payloads.
Ionizable Lipid 4 V103658 Ionizable Lipid 4 1799316-81-6 Ionizable lipid 4 is an ionizable cationic lipid and is also the product of the hydrogen peroxide-induced rearrangement of cationic lipid CA-lipid 5.
Ionizable lipid Az1 V97436 Ionizable lipid Az1 Ionizable lipid Az1 is an ionizable lipid that reacts with a variety of terminal alkynes under standard CuAAC conditions.
ionizable lipid-1 V74050 ionizable lipid-1 2055939-68-7 Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure.
Ionizable lipid-1 hydrochloride V80392 Ionizable lipid-1 hydrochloride Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure.
Ionizable lipid-2 V87542 Ionizable lipid-2 2763904-72-7 Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construction of lipid nanoparticles (LNPs).
IR-117-17 V93291 IR-117-17 2940241-38-1 IR-117-17 is an ionizable cationic amino lipid that acts on the respiratory tract.
Itaconic acid-13C5 (Itaconic acid 13C5) V82218 Itaconic acid-13C5 (Itaconic acid 13C5) 2095777-38-9 Itaconic acid-13C5 is 13C (carbon 13) labelled Itaconic acid.
IZ-Chol V93235 IZ-Chol 191990-35-9 IZ-Chol (IZ-cholesterol) is an ionizable cationic lipid containing cholesterol.
L-369 V103077 L-369 1443522-24-4 L-369 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles and deliver mRNA.
L16 V98383 L16 L16 is an ionizable lipid.
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