Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V73433 | Gal-C4-Chol | 219850-70-1 | Gal-C4-Chol is a glycosylated cholesterol analogue. |
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V79572 | Genevant CL1 monohydrochloride | Genevant CL1 mono HCl is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery. | |
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V76978 | GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) | GL67 (N4-Spermine cholesteryl carbamate) (penta HCl) is a cationic lipid. | |
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V90138 | Glucosamine Cholesterol | 1257309-90-2 | Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate that can be used to prepare lipid nanoparticles (LNPs). |
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V87546 | HAPC-Chol | 1027801-73-5 | HAPC-Chol is a cationic cholesterol that can be used as a component of liposome complexes. |
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V93283 | HAPC-Chol hydroiodide | HAPC-Chol is a cationic cholesterol that can be used as a component of liposome complexes. | |
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V73419 | Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate | 2714482-26-3 | Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate may be utilized in liposome delivery systems for the delivery of mRNA vaccines. |
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V98336 | IAJD249 | IAJD249 is an ionizable lipid. | |
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V98223 | IAJD93 | IAJD93 is an ionizable lipid. | |
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V93307 | IM21.7c | 2416939-42-7 | IM21.7c is a cationic lipid that can be used to synthesize lipid nanoparticles (LNPs) for the delivery of mRNA and other payloads. |
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V103658 | Ionizable Lipid 4 | 1799316-81-6 | Ionizable lipid 4 is an ionizable cationic lipid and is also the product of the hydrogen peroxide-induced rearrangement of cationic lipid CA-lipid 5. |
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V97436 | Ionizable lipid Az1 | Ionizable lipid Az1 is an ionizable lipid that reacts with a variety of terminal alkynes under standard CuAAC conditions. | |
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V74050 | ionizable lipid-1 | 2055939-68-7 | Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure. |
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V80392 | Ionizable lipid-1 hydrochloride | Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure. | |
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V87542 | Ionizable lipid-2 | 2763904-72-7 | Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construction of lipid nanoparticles (LNPs). |
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V93291 | IR-117-17 | 2940241-38-1 | IR-117-17 is an ionizable cationic amino lipid that acts on the respiratory tract. |
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V82218 | Itaconic acid-13C5 (Itaconic acid 13C5) | 2095777-38-9 | Itaconic acid-13C5 is 13C (carbon 13) labelled Itaconic acid. |
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V93235 | IZ-Chol | 191990-35-9 | IZ-Chol (IZ-cholesterol) is an ionizable cationic lipid containing cholesterol. |
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V103077 | L-369 | 1443522-24-4 | L-369 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles and deliver mRNA. |
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V98383 | L16 | L16 is an ionizable lipid. |