Glucokinase is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate.Humans and the majority of other vertebrates have cells in their liver, pancreas, gut, and brain that contain glucokinase. It functions as a glucose sensor in each of these organs, signaling changes in metabolism or cell function in response to rising or falling blood glucose levels, such as those that happen after meals or during fasting. Since glucosekinase has a lower affinity for glucose than the other hexokinases do and concentrates its activity in a small number of cell types, the other three hexokinases are more crucial glucose preparers for most tissues' and organs' glycolysis and glycogen synthesis.Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V78507 | α-Glucosidase-IN-34 | α-Glucosidase-IN-34 (compound 7f) is a potent α-glucosidase inhibitor (IC50= 2.90 μM) and may be utilized in the study of type 2 diabetes and hyperglycemia. | |
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V81792 | α-Glucosidase-IN-36 | α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor (antagonist) with IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. | |
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V78325 | α-Glucosidase-IN-38 | α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor (antagonist) with IC50 of 12.44±0.38 μM. | |
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V80169 | α-Glucosidase-IN-39 | α-Glucosidase-IN-39 is a potent inhibitor of α-glucosidase enzyme with IC50 of 869.06 ppm. | |
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V81793 | α-Glucosidase-IN-40 | α-Glucosidase-IN-40 (compound 5) is a noncompetitive α-glucosidase enzyme inhibitor (antagonist) with IC50 of 24.62 μM. | |
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V79944 | α-Glucosidase-IN-41 | α-Glucosidase-IN-41 (compound 5o) is a potent α-glucosidase (α-glucosidase) inhibitor. | |
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V81794 | α-Glucosidase-IN-42 | α-Glucosidase-IN-42 (Compound 26) is a 9-O-berberubin carboxylic acid analogue. | |
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V78625 | α-Glucosidase-IN-43 | α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50= 4.32 μM) with acute hypoglycemic activity. |
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