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Drug Metabolite

Drug Metabolite

Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite. 

Drug Metabolite related products

Structure Cat No. Product Name CAS No. Product Description
RL-603 V91144 RL-603 444904-63-6 RL-603 is a metabolite of Anagrelide.
Rosuvastatin lactone V72213 Rosuvastatin lactone 503610-43-3 Rosuvastatin lactone is a metabolite of rosuvastatin, an HMG-CoA inhibitor.
RP101075 V72157 RP101075 1306760-73-5 RP101075, the bioactive metabolite of Ozanimod, is a potent oral S1PR1 agonist/activator with EC50 of 0.27 nM.
RP101442 V72241 RP101442 1306761-08-9 RP101442, the bioactive metabolite of Ozanimod, is a selective S1PR1 agonist/activator with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively.
RP101988 V76549 RP101988 2990018-57-8 RP101442 is the main bioactive metabolite of Ozanimod and a selective S1PR1 agonist/activator with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1P5R respectively.
RPR132595A hydrochloride (NPC hydrochloride) V76548 RPR132595A hydrochloride (NPC hydrochloride) RPR132595A (NPC) HCl is the bioactive metabolite of CPT-11, which is produced by cytochrome P-450 3A4 (CYP3A4) and is ultimately excreted in the urine.
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine V107226 S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine 364083-21-6 Sulforaphane metabolite S-(N-methylsulfinylbutylthiocarbamoyl)-L-cysteine (SF-cysteine) can enhance the survival rate of Nalm-6 cells.
S-Allylmercapturic acid V72172 S-Allylmercapturic acid 23127-41-5 S-Allylmercapturic acid is a biomarker of garlic consumption food intake (BFI).
Saluamine V101727 Saluamine 3086-91-7 Saluamine is a metabolite of furosemide.
Saluamine (Standard) V97010 Saluamine (Standard) 3086-91-7 Saluamine (Standard) is the analytical standard for Saluamine.
Seco Rapamycin (Secorapamycin; Secorapamycin A) V72298 Seco Rapamycin (Secorapamycin; Secorapamycin A) 147438-27-5 Seco Rapamycin (Secorapamycin A) is the open-ring metabolite of Rapamycin.
Seco Rapamycin ethyl ester V76525 Seco Rapamycin ethyl ester Seco Rapamycin ethyl ester is the open-ring metabolite of Rapamycin.
Silodosin Glucuronide sodium V101659 Silodosin Glucuronide sodium 879292-24-7 Silodosin β-D-glucuronide is a metabolite of silodosin.
Sofosbuvir impurity B (sofosbuvir impurity B) V76496 Sofosbuvir impurity B (sofosbuvir impurity B) Sofosbuvir impurity B is an impurity in Sofosbuvir.
Sofosbuvir impurity D V76495 Sofosbuvir impurity D Sofosbuvir impurity D is an impurity in Sofosbuvir.
Sofosbuvir impurity E (sofosbuvir impurity E) V76494 Sofosbuvir impurity E (sofosbuvir impurity E) Sofosbuvir impurity E is an impurity in Sofosbuvir.
T-705RMP V72199 T-705RMP 356783-08-9 T-705RMP is the phosphorylated metabolite of T-705 and has a weak inhibitory effect on host cell IMP dehydrogenase (IMPDH) activity, with IC50 of 601 μM.
T-705RMP ammonium V103121 T-705RMP ammonium 2096342-42-4 T-705RMP (ammonium) is the ammonium salt form of T-705RMP, which has a weak inhibitory effect on the activity of host cell IMP dehydrogenase (IMPDH).
Tamoxifen N-oxide V72156 Tamoxifen N-oxide 75504-34-6 Tamoxifen N-oxide is a metabolite of Tamoxifen.
TBBPA-sulfate V103336 TBBPA-sulfate 902525-22-8 TBBPA-sulfate is a metabolite of TBBPA.
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