The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V53221 | Trecovirsen (GEM91) | 153021-75-1 | Trecovirsen (GEM91) is an antisense oligonucleotide targeting the HIV gag gene. |
|
V89685 | Trecovirsen sodium | Trecovirsen sodium is an antisense oligonucleotide targeting the HIV gag gene. | |
|
V52922 | Trovirdine (Travirdine; LY300046) | 149488-17-5 | Trovirdine inhibits HIV-1 reverse transcription with IC50 of 7 nM. |
|
V54284 | Tsugafolin | 66568-97-6 | Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and no cytotoxic effect (<150 μM). |
|
V88267 | Tucaresol | 84290-27-7 | Tucaresol is an orally bioavailable immunopotentiating drug that enhances T helper cell activity and induces increased IL-2 and IFN-γ levels in mice and humans. |
|
V114565 | U-96988 | 149394-65-0 | U-96988 (PNU-96988) is a non-peptide HIV-1 protease inhibitor with a Ki value of 38 nM. |
|
V85029 | Uncaric acid (6β,19α-Dihydroxyursolic acid) | 123135-05-7 | |
|
V111201 | Urushiol (15:3) | 83543-37-7 | Urushiol (15:3) (compound 4) is a urushiol compound found in the leaves of the lacquer tree (Rhus verniciflua). |
|
V81736 | VIR-165 | VIR-165 is a modified form of a viral inhibitory peptide (VIRIP) that binds to a fusion peptide of the gp41 subunit and prevents its entry into target membranes. | |
|
V101755 | VIRIP | 339332-64-8 | VIRIP (human α1-AT(353-372)) is an HIV-1 inhibitor. |
|
V54243 | Wilfortrine (triptolide) | 37239-48-8 | Wilfortrine is a bioactive sesquiterpene alkaloid. |
|
|
V116787 | Zintevir | 171345-51-0 | Zintevir is an antisense oligonucleotide that targets HIV-1 integrase. |
|
|
V116795 | Zintevir sodium | Zintevir sodium is an antisense oligonucleotide that targets HIV-1 integrase. | |
|
V76070 | β-Rubromycin | 27267-70-5 | β-Rubromycin is a potent and specific inhibitor of human immunodeficiency virus-1 (HIV-1) RNA-directed DNA polymerase (reverse transcriptase). |
|
V40231 | Amphotericin B methyl ester | 36148-89-7 | Amphotericin B methyl ester, the methyl ester derivativeof Amphotericin B (A-634250), is a cholesterol-binding compound with potent antifungal activity. |
|
V4389 | ISLATRAVIR | 865363-93-5 | Islatravir (formerly known as MK-8591; 4′-ethynyl-2-fluoro-2′-deoxyadenosine; EFdA;ISL) is a novel and potent anti-HIV-1agent which acts as an NRTTI (nucleosidereverse transcriptaseinhibitor) with anti-HIV activities. |
|
V20470 | Elsulfavirine | 868046-19-9 | Elsulfavirine is a reverse transcriptase inhibitor for HIV-1 infection and a new active molecule against HIV. |
|
V9288 | Gardiquimod diTFA | 1159840-61-5 | Gardiquimod diTFA is a TLR7/8 agonist and an imidazoquinoline analog. |
|
V3503 | Temsavir | 701213-36-7 | Temsavir (formerly known as BMS626529; BMS-626529) is a novel, potent attachment inhibitor that targetsHIV-1gp120 and prevents its binding to CD4+T cells. |
|
V3874 | doravirine | 1338225-97-0 | Doravirine (formerlyknown as MK-1439 and DOR; trade name:Pifeltro) is a novel human immunodeficiency type 1 virus (HIV-1) nonnucleoside reverse transcriptase inhibitor (NNRTI) that is approved in August 2018 to treat HIV-1 infection in adult patients. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
