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Parasite

Parasite

Antiparasitics are a group of drugs used to treat illnesses caused by parasites like nematodes, cestodes, trematodes, and infectious protozoa.

Parasite related products

Structure Cat No. Product Name CAS No. Product Description
MED6-189 V93730 MED6-189 2650073-66-6 MED6-189 is a kalihinol analog that disrupts acrosomal function and vesicle trafficking in Plasmodium falciparum (IC50 < 50 nM).
Melicopine V107147 Melicopine 568-01-4 Melicopine is an alkaloid found in Pseudomonas aeruginosa with antimalarial and anticancer activities.
Menoctone V93292 Menoctone 14561-42-3 Menaquinone is an oral antimalarial drug that inhibits blood-borne malaria in rodents.
Methylclonazepam V107106 Methylclonazepam 5527-71-9 Methylclonazepam is a benzodiazepine with anxiolytic properties.
Milbemycin A4 oxime V102128 Milbemycin A4 oxime 93074-04-5 Milbemycin A4 oxime (5-ketomilbemycin A4 oxime; 5-oxomilbemycin A4 5-oxime) is a derivative of milbemycin A4 and a component of milbemycin oxime, both of which have insecticidal and nematicidal activities.
ML471 V99893 ML471 2226227-77-4 ML471 is an orally active inhibitor of parasite tyrosyl-tRNA synthetase (PfTyrRS) used in malaria research.
MMV006833 V89721 MMV006833 701253-55-6 MMV006833 is an inhibitor of Plasmodium falciparum MMV006833 targets the lipid transfer protein PfSTART1 and inhibits the ring stage development of Plasmodium falciparum.
MMV03 V104805 MMV03 375394-80-2 MMV03 is an antimalarial compound that is effective against Plasmodium falciparum (EC50: 0.6 μM).
MMV1557817 V88307 MMV1557817 2065197-82-0 MMV1557817 is an orally active antimalarial agent.
MMV1634566 V101228 MMV1634566 MMV1634566 is a potent antimalarial drug.
N-Methyltaurine V106848 N-Methyltaurine 107-68-6 N-methyltaurine is a taurine-derived metabolite with a minimum effective concentration of 10 μM for maintaining hamster sperm motility.
NMT-IN-3 V103580 NMT-IN-3 NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT).
NPD8790 V87605 NPD8790 615281-26-0 NPD8790 is a selective mitochondrial respiratory complex I inhibitor with an IC50 of 2.4 µM for Caenorhabditis elegans complex I.
Omphalotin A V91027 Omphalotin A 186511-50-2 Omphalotin A is a cyclic peptide with nematicidal activity.
Orfamide A V102293 Orfamide A 939960-34-6 Orfamide A is the major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity.
Pentadecane V90800 Pentadecane 629-62-9 Pentadecane is a floral volatile antimalarial agent that inhibits the growth of parasites such as Leishmania and prevents infection of macrophages.
PfCLK3-IN-1 V103710 PfCLK3-IN-1 PfCLK3-IN-1 (compound 4) acts as a covalent inhibitor of Plasmodium falciparum CLK3 (Pf CLK3) under alkaline conditions with a pEC50 of 7.1.
PFK-IN-1 V102904 PFK-IN-1 735303-62-5 PFK-IN-1 (Compound 1) is a phosphofructokinase PFK inhibitor with IC50 of 0.41 and 0.23 μM for Trypanosoma brucei and Trypanosoma cruzi PFK, respectively, and ED50 of 15.18 μg/mL for Trypanosoma brucei.
PfPKG-IN-2 V103780 PfPKG-IN-2 PfPKG-IN-2 (Compound 53) is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with IC50 of 13 nM.
Pheanthine V90860 Pheanthine 1263-79-2 Pheanthine (Compound 2) is an antimalarial drug that inhibits chloroquine-resistant Plasmodium falciparum strain K-1 (IC50 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 0.03 μM).
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