The role of tau as a microtubule-associated protein in neurons is well established. They play major roles in preserving the stability of microtubules in axons and are widely distributed in central nervous system (CNS) neurons. However, in a variety of neurodegenerative disorders collectively known as tauopathies, aberrant assembly of tau into insoluble aggregates is accompanied by synaptic dysfunction and neural cell death.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V121804 | (E/Z)-Florzolotau | (E/Z)-Florzolotau is a mixed configuration or an unspecified configuration of Florzolotau. | |
|
V70072 | (R)-TTBK1-IN-1 | 2735015-59-3 | TTBK1-IN-1 is a specific, brain-penetrating inhibitor of tau tubulin kinase 1 (TTBK1). |
|
V70076 | (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) | 2022956-55-2 | (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) is a bioactive peptide discovered by peptide screening. |
|
V70090 | (Ser(PO3H2)396,404)-Tau Peptide (379-408) | 2022956-60-9 | (Ser(PO3H2)396,404)-Tau Peptide (379-408) is a bioactive peptide discovered by peptide screening. |
|
V70099 | (Thr(PO3H2)231)-Tau Peptide (225-237) | 1670270-09-3 | (Thr(PO3H2)231)-Tau Peptide (225-237) is a fragment of the tau peptide. |
|
V70107 | Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 | 2858785-68-7 | Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 is serum stable, nontoxic to nerve cells, and can selectively inhibit tau fibrosis. |
|
V70087 | Acetyl-PHF5 amide | 1190970-24-1 | Acetyl-PHF5 amide is an amyloid tau peptide. |
|
V77297 | Acetyl-PHF6 amide TFA (AcPHF6 TFA; Ac-VQIVYK-NH2 TFA) | Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau-derived hexapeptide. | |
|
V70096 | Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) | 2022956-56-3 | Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) is a bioactive peptide discovered by peptide screening. |
|
V128154 | AChE/MAO-B-IN-9 | 2341935-88-2 | AChE/MAO-B-IN-9 is an orally effective selective, reversible, non-competitive acetylcholinesterase (AChE) and monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.156 μM against AChE in electric eel. |
|
V114571 | ACI-3024 | 2361566-66-5 | ACI-3024 is an orally effective and highly selective Tau protein aggregation inhibitor. |
|
V128681 | AMG28 | 1202764-07-5 | AMG28 is an ATP-competitive inhibitor that targets TTBK1 and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. |
|
V129275 | APNmAb005 | APNmAb005 is a human monoclonal antibody (mAb) that targets MAPT/Tau/PHF-tau. | |
|
V129444 | Armanezumab | Armanezumab is a pathological tau protein inhibitor that specifically binds to the N-terminal domain exposed by pathological tau protein (eptopic covering amino acids 4-8: PRQEF). | |
|
V70068 | ASN90 | 1884154-02-2 | ASN90 is an orally bioactive and specific O-GlcNAcase (OGA) enzyme inhibitor (antagonist) with IC50 of 10.2 nM. |
|
V110342 | Aβ/tau aggregation-IN-4 | 3105860-83-8 | Aβ/tau aggregation inhibitor-IN-4 (compound D21) is an Aβ/tau aggregation inhibitor. |
|
V129930 | BChE-IN-41 | BChE-IN-41 is a highly selective butyrylcholinesterase (BChE) inhibitor (IC50 = 12 nM, Ki = 6.6 nM). | |
|
V130115 | BF-170 | 22191-97-5 | BF-170 is a selective tau protein filament binder with an EC50 value of 221 nM. |
|
V130162 | BIIB076 | BIIB076 is a human monoclonal antibody (mAb) that targets PHF-tau. | |
|
V70073 | BSc3094 | 946857-84-7 | BSc3094 is a Tau aggregation inhibitor. |
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