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Beta Amyloid

Beta Amyloid

As the primary component of the amyloid plaques seen in the brains of Alzheimer patients, amyloid- (A) refers to peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease. The amyloid precursor protein (APP), which is cut by specific enzymes to produce A, produces the peptides. Amyloid molecules can group together to create a variety of flexible, soluble oligomers.A amyloid-peptide buildup results from excessive A production or malfunctioning clearance mechanisms. Amyloid- forms diffuse and neuritic plaques in the parenchyma and blood vessels by self-aggregating into oligomers of various sizes. Strong synaptotoxins, proteasome inhibition, mitochondrial inhibition, alteration of intracellular Ca2+ levels, and induction of inflammatory processes are all characteristics of amyloid-oligomers and plaques. Neuronal dysfunction is also thought to be influenced by the loss of A's typical physiological functions.

Beta Amyloid related products

Structure Cat No. Product Name CAS No. Product Description
(Gln22)β-Amyloid (1-40) human TFA V121819 (Gln22)β-Amyloid (1-40) human TFA (Gln22)β-Amyloid (1-40) human TFA is a peptide containing amyloid β protein (Aβ) used in Alzheimer's disease research.
(Mor-Cor)Ag(III) V121833 (Mor-Cor)Ag(III) (Mor-Cor)Ag(III) is a silver(III) porphyrin complex that can penetrate the blood-brain barrier.
2,3-Dehydrosilybin A V71438 2,3-Dehydrosilybin A 25166-14-7 2,3-Dehydrosilybin A is a longevity-promoting and anti-aggregation compound.
2-Hydroxy-5-(phenyldiazenyl)benzoic acid-d5 V71371 2-Hydroxy-5-(phenyldiazenyl)benzoic acid-d5 1331662-16-8 2-Hydroxy-5-(phenyldiazenyl)benzoic acid-d5 is deuterated labeled 2-Hydroxy-5-(phenyldiazenyl)benzoic acid.
2002-G12 V104737 2002-G12 313666-93-2 2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%.
4-Sulfocalix[4]arene V111853 4-Sulfocalix[4]arene 112269-92-8 4-Sulfocalix[4]arene (p-sulfonocalix[n]arene) is an amyloid β42 (amyloid β42) binder with a Kd value of 5.39 M.
5-FAM-β-Amyloid (1-28) V126972 5-FAM-β-Amyloid (1-28) 5-FAM-β-Amyloid (1-28) is a fluorescently labeled β-amyloid protein (1-28).
5-FAM-β-Amyloid (1-42), human TFA (5-FAM-Amyloid β-peptide (1-42) (human) TFA) V77650 5-FAM-β-Amyloid (1-42), human TFA (5-FAM-Amyloid β-peptide (1-42) (human) TFA) 5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a 5-FAM-labeled β-Amyloid (1-42), human (TFA).
5-FAM-β-Amyloid (1-42), human Tris V126973 5-FAM-β-Amyloid (1-42), human Tris 5-FAM-β-Amyloid (1-42), human Tris is a 5-FAM-labeled β-amyloid protein (1-42), human TFA.
5-FAM-β-Amyloid (1-42), human Tris (5-FAM-Amyloid β-peptide (1-42) (human) Tris) V86199 5-FAM-β-Amyloid (1-42), human Tris (5-FAM-Amyloid β-peptide (1-42) (human) Tris)
6′-Methyl paeonol V83543 6′-Methyl paeonol 6540-66-5
7-Deoxy-trans-dihydronarciclasine V71443 7-Deoxy-trans-dihydronarciclasine 145987-74-2 7-Deoxy-trans-dihydronarciclasine is an alkaloid and an inhibitor (blocker/antagonist) of tobacco mosaic virus (TMV) (IC50= 1.80 μM).
[Ala28]-β Amyloid(25-35) (β(25-35)KA) V71439 [Ala28]-β Amyloid(25-35) (β(25-35)KA) 173993-86-7 [Ala28]-β Amyloid(25-35) (β(25-35)KA) is an electroneutral mutant peptide of Aβ(25-35) that accelerates the aggregation of firefly luciferase.
[Ala28]-β Amyloid(25-35) TFA V114718 [Ala28]-β Amyloid(25-35) TFA [Ala28]-β amyloid(25-35) (β(25-35)KA) TFA is an electronegative mutant peptide of Aβ(25-35) that can accelerate the aggregation of firefly luciferase.
[Arg6]-β-Amyloid (1-40), england mutation V71378 [Arg6]-β-Amyloid (1-40), england mutation 1802084-26-9 [Arg6]-β-Amyloid (1-40), england mutation is a biologically active peptide.
[Arg6]-β-Amyloid (1-42), england mutation V77472 [Arg6]-β-Amyloid (1-42), england mutation [Arg6]-β-Amyloid (1-42), england mutation is a biologically active peptide.
[Asn23] β-Amyloid (1-40), Iowa mutation V71392 [Asn23] β-Amyloid (1-40), Iowa mutation 374796-72-2 [Asn23] β-Amyloid (1-40), Iowa mutation is a biologically active peptide.
[Asn23]-beta-Amyloid (1-42), iowa mutation V77473 [Asn23]-beta-Amyloid (1-42), iowa mutation [Asn23]-beta-Amyloid (1-42), iowa mutation is a biologically active peptide.
[D-Ser14]-Humanin V92286 [D-Ser14]-Humanin 570382-85-3 [D-Ser14]-Humanin is a biologically active peptide in which the Ser14 residue of humanin is changed from L-form to D-form.
AAKLVFF V113880 AAKLVFF 1038400-67-7 AAKLVFF is an oligopeptide that can self-assemble into nanotubes.
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