Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V74486 | MRE-269-d7 (ACT-333679-d7) | 1265295-20-2 | MRE-269-d7 is the deuterium labelled form of MRE-269 . |
|
V91727 | MRE-269-d7 sodium | 2249828-87-1 | MRE-269-d7 (ACT-333679-d7) sodium is deuterated MRE-269. |
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V83606 | N-Cyclopropyl bimatoprost | 1138395-12-6 | |
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V101867 | N-Cyclopropyl methyl bimatoprost | 1138395-10-4 | N-Cyclopropylmethylbimatoprost (17-phenyltrinorprostaglandin F2α cyclopropylmethylamide) is an analog of PGF2α. |
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V37610 | NTP42 | 2055599-51-2 | NTP42 is a novel thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. |
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V79159 | NXT-10796 | NXT-10796 is an orally bioactive entero-restricted EP4 receptor agonist (activator). | |
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V102046 | ONO 207 | 27376-74-5 | ONO 207 (13,14-dihydroprostaglandin; 13,14-dihydroPGF2α) is a PGF2α analog without unsaturation in the lower side chain. |
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V76681 | ONO-8711 dicyclohexylamine | ONO-8711 dicyclohexylamine is a potent and specific competitive EP1 antagonist (inhibitor) with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively. | |
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V74477 | ONO-8713 | 459411-08-6 | ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist. |
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V4681 | ONO-AE3-208 | 402473-54-5 | ONO-AE3-208 is a novel and potent EP4 antagonist with Ki of 1.3 nM. |
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V74465 | PDC31 (THG113.31; ILGHXDYK) | 634586-40-6 | PDC31 (THG113.31; ILGHXDYK) is an allosteric and noncompetitive inhibitor of the FP Prostaglandin Receptor. |
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V74467 | Pexopiprant | 932708-14-0 | Pexopiprant is an oral antagonist of prostaglandin D2 receptor 2 (DP2) with Ki < 100nM. |
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V1881 | PF-04418948 | 1078166-57-0 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist. |
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V7294 | PGD2-IN-1 | 885066-67-1 | PGD2-IN-1 is a DP receptor blocker (antagonist), disclosed in patent WO 2006044732 A2, example compound 15 (d), with IC50 of 0.3 nM. |
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V88943 | PGDM | 133161-96-3 | PGDM (Prostaglandin D Metabolite) is the major urinary metabolite of prostaglandin D2 and is prone to reversible cyclization. |
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V102491 | PGF2α-isopropyl ester | 53764-90-2 | PGF2α-isopropyl ester is a derivative of the prostaglandin receptor PGF2α, which can reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor from the uveosclera. |
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V86150 | PGN-9856 | 863704-91-0 | |
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V27653 | Pizuglanstat | 1244967-98-3 | Pizuglanstat is a novel and potent prostaglandin D synthase inhibitor with the potential forDuchenne muscular dystrophy (DMD). |
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V101254 | Pizuglanstat hydrate | 1584160-52-0 | Pittsburghstat hydrate (TAS-205) is a hematopoietic prostaglandin D synthase (HPGDS) inhibitor. |
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V89661 | Prostaglandin D2 methyl ester | 49852-81-5 | Prostaglandin D2 methyl ester is a prodrug form of prostaglandin D2. |
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