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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
V80126 2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine 2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine is an analogue of purine nucleoside.
V77546 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine is an analogue of purine nucleoside.
V79514 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine is an analogue of purine nucleoside.
V80382 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine is a uridine analog.
V80383 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine is an analogue of purine nucleoside.
V80046 2'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine 2'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine is an analogue of purine nucleoside.
V79305 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate (triethylammonium) is an analogue of purine nucleoside.
V79304 2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium 2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium is an analogue of purine nucleoside.
V77548 2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium 2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium is an analogue of purine nucleoside.
V77549 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate (triethylamine) is an analogue of purine nucleoside.
V77551 2'-O,4'-C-Methyleneadenosine 5'-monophosphate triethylammonium 2'-O,4'-C-Methyleneadenosine 5'-monophosphate (triethylammonium) is an analogue of purine nucleoside.
V77550 2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium 2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate (ammonium) is an analogue of purine nucleoside.
V80416 2'-O-(3-Azidopropyl)-5-azacytidine 2'-O-(3-Azidopropyl)-5-azacytidine is an analogue of purine nucleoside.
V79614 2'-O-Acetyl-5'-O-benzoyl-3'-O-(2-methoxyethyl) uridine 2'-O-Acetyl-5'-O-benzoyl-3'-O-(2-methoxyethyl) uridine is a uridine analog.
V77553 2'-O-Me-5-IU-3'-phosphoramidite 2'-O-Me-5-IU-3'-phosphoramidite is an analogue of purine nucleoside.
V77554 2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium 2'-O-Methyl-5-methyluridine 5'-triphosphate (triethylammonium) is a thymidine analog.
V77555 2'-O-Methyladenosine 5'-monophosphate triethyl ammonium 2'-O-Methyladenosine 5'-monophosphate triethyl ammonium is an adenine nucleoside analogue.
V80111 2,6-Bis(4-morpholinyl)-9-bD-ribofuranosyl-9H-purine 2,6-Bis(4-morpholinyl)-9-bD-ribofuranosyl-9H-purine is an adenine nucleoside analogue.
V80158 2-(3-Methyln-propylidene hydrazino)adenosine 2-(3-Methyln-propylidene hydrazino) adenosine is an analogue of purine nucleoside.
V80007 2-(P-Cyanophenyl methylidene hydrazino) adenosine 2-(P-Cyanophenyl methylidene hydrazino) adenosine is an analogue of purine nucleoside.
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