Kinesin

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Kinesin

Kinesins are a family of molecular motors that use the energy of ATP hydrolysis to move along the surface of, or destabilize, microtubule filaments.In humans, there are 45 kinesin proteins spread across 14 different subclasses of the kinesin motor protein family. It has been established that many of these proteins—or their orthologues—have crucial roles to play in both the mitotic and meiotic cell cycles. Based on where their motor domains are located, kinesins can also be divided into three groups: internal, C-terminal, and N-terminal kinesins. Traditional kinesin moves in a coordinated, hand-over-hand manner along a microtubule protofilament, acting as a dimer.

Kinesins play critical roles in the progression of the cell cycle, cytokinesis, spindle formation, microtubule dynamics, and chromosome segregation. Kinesins typically play roles in diseases involving pathogen transport, pathogen transport defects, or cell division.

Kinesin related products

Cat No.	Product Name	CAS No.	Product Description
V104468	PROTAC KSP-IN-1		PROTAC KSP-IN-1 (Compound 21) is a PROTAC kinesin (KSP) degrader that degrades KSP in HCT-116 with a DC50 of 114.8 nM.
V54365	PVZB1194	1141768-04-8	PVZB1194 is a biphenyl-type inhibitor of the kinase spindle protein Eg5 or KIF11.
V54366	solidagonic acid	19941-91-4	Solidagonic acid inhibits HSET motor activity by promoting the transition of abnormal unipolar spindles to bipolar spindles.
V4905	Litronesib	910634-41-2	Litronesib (formerly also known as LY2523355; LY-2523355; KF-8961) is a novel, potent and selective inhibitor of the kinesin-related motor protein Eg5 with potential anticancer activity.
V2718	Monastrol	329689-23-8	Monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cell lines.
V4726	Filanesib (ARRY520)	885060-09-3	Filanesib (formerly also known as ARRY-520) is a novel, potent and synthetic small molecule inhibitor of kinesin spindle protein (KSP) with anticancer activity.