Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V53257 | Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside (decitabine impurity 2) | 4330-34-1 | Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside is an analogue of purine nucleoside. |
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V55459 | Methyl 3'-O-benzyl xyloriboside | 201014-45-1 | Methyl 3'-O-benzyl xyloriboside is an analogue of purine nucleoside. |
|
V55479 | Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside | 636581-81-2 | Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside is a ribofuranosyl nucleoside analog. |
|
V55330 | Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside | 55797-67-6 | Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is an analogue of purine nucleoside. |
|
V75769 | Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate | 70255-70-8 | Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is an analogue of purine nucleoside. |
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V84372 | MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite | 2645354-88-5 | |
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V75660 | N,N-Dimethyl-2′-O-methyladenosine | 30891-53-3 | N,N-Dimethyl-2′-O-methyladenosine is an analogue of purine nucleoside. |
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V55560 | N,N-Dimethyl-2'-O-methylcytidine | 34218-81-0 | N,N-Dimethyl-2'-O-methylcytidine is an analogue of purine nucleoside. |
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V55290 | N-(1-Oxopropyl)cytidine | 60107-04-2 | N-(1-Oxopropyl)cytidine is a cytosine nucleoside analog. |
|
V55901 | N-(2-Phenoxyacetyl)adenosine | 119824-65-6 | N-(2-Phenoxyacetyl)adenosine is an adenine nucleoside analogue. |
|
V51795 | N-(2-Phenoxyacetyl)guanosine | 119824-66-7 | N-(2-Phenoxyacetyl)guanosine is an analog of guanosine. |
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V75742 | N-(3-Methylbutyl)adenosine | 17659-78-8 | N-(3-Methylbutyl)adenosine is an adenine nucleoside analog. |
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V55452 | N-6-Methyl-2-deoxyadenosine ((2R,3S,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3-ol ) | 2002-35-9 | N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analog. |
|
V75606 | N-[(3-Methoxyphenyl)methyl]adenosine | 101565-95-1 | N-[(3-Methoxyphenyl)methyl]adenosine is an adenine nucleoside analogue. |
|
V55942 | N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine | 937205-20-4 | N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanine nucleoside analogue. |
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V55803 | N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine | 722505-71-7 | N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenine nucleoside analog. |
|
V55699 | N-Acetyl-2′-deoxycytidine (N4-Acetyl-2′-deoxycytidine) | 32909-05-0 | N-Acetyl-2′-deoxycytidine is an analogue of purine nucleoside. |
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V55960 | N-Acetyladenosine | 16265-37-5 | N-Acetyladenosine is an adenine nucleoside analogue. |
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V55838 | N-Benzoyl-2′-O-2-propyn-1-yladenosine | 210096-44-9 | N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenine nucleoside analogue. |
|
V55506 | N-Benzoyl-3′-O-methyladenosine | 85090-30-8 | N-Benzoyl-3′-O-methyladenosine is an analogue of purine nucleoside. |
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