| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0244 | A-769662 | 844499-71-4 | A-769662 (A769662;A 769662), a thienopyridone analog, is a potent, alloesteric and reversible activator of AMPK (AMP-activated protein kinase)with antidiabetic activity. |
|
V52430 | Aldometanib (LXY-05-029) | 2904601-67-6 | Aldometanib (LXY-05-029) is an aldolase inhibitor. |
|
V77269 | AMARA peptide TFA | AMARA peptide (TFA) is a substrate of salt-induced kinase (SIK) and adenylate-activated protein kinase (AMPK). | |
|
V52421 | AMPK activator 11 | 2948304-00-3 | AMPK activator 11 is an AMP-activated protein kinase activator with nano-level anti-tumor activity and can resist a variety of CRC. |
|
V52419 | AMPK-IN-1 | 1219739-95-3 | AMPK-IN-1 is an AMPK activator (EC50 551 nM for isoform α2β2γ1). |
|
V105419 | AMPK-IN-6 | AMPK-IN-6 (Compound 13a) is a potent AMPK inhibitor with IC50 of 0.093 µM. | |
|
V70222 | AMPK-α1β1γ1 activator 1 | 1943510-86-8 | AMPK-α1β1γ1 activator 1 (M1) is the acylglucuronide metabolite of the Indole-3-cancer-based AMPK activator. |
|
V2166 | ASP4132 tosylate | 1640294-30-9 | ASP4132 tosylate (ASP-4132) is an oral bioavailable AMPK activator (EC50 = 18 nM) with potential anticancer activity. |
|
V129540 | ASS1 activator 1 | ASS1 activator 1 is an ASS1 activator with an EC50 value of 1.90 μM. | |
|
V2440 | BC1618 | 2222094-18-8 | BC1618, an orally bioactive Fbxo48 inhibitor, stimulates Ampk signaling (preventing activated pAmpkα from being degraded by the Fbxo48-mediated proteasome). |
|
V118940 | Biotin-AMPKα2β1γ1 Recombinant Human Active Protein Kinase | AMPK is an αβγ heterotrimeric serine/threonine kinase that can be activated by decreasing adenosine triphosphate (ATP) concentration and increasing AMP concentration. | |
|
V120236 | Candidusin A | 81474-59-1 | Candiduxin A (CHNQD-0803) (compound 4) is an AMPK activator with a KD value of 47.28 nM. |
|
V3967 | EX-229 | 1219739-36-2 | EX229 (EX-229; AMPK Activator 991), a benzimidazole analog, is a novel, potent and allosteric AMPK (AMP-activated protein kinase) activator with Kd values of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively. |
|
V0249 | GSK621 | 1346607-05-3 | GSK621 is a novel, potent and selective activator of AMP-activated protein kinase (AMPK) with potential antitumor activity. |
|
V0250 | HTH-01-015 | 1613724-42-7 | HTH-01-015 is a novel, potent and selective inhibitor of NUAK1( (NUAK family SnF1-like kinase-1)which can serve as useful chemical probes to delineate the biological roles of the NUAK kinases. |
|
V88834 | KHKI-01128 | KHKI-01128 is a NUAK2 inhibitor with IC50 of 0.024 μM. | |
|
V76788 | MARK4 inhibitor 2 | MARK4 inhibitor 2 is an inhibitor (blocker/antagonist) of microtubule affinity-regulated kinase 4 (MARK4), with a Km value of 6.3×107 and IC50 of 0.82 μM. | |
|
V4058 | MK-3903 | 1219737-12-8 | MK-3903 (MK3903) is a novel, potent and selectiveAMPK (AMP-activated protein kinase)activator with EC50 of 8 nM for α1 β1 γ1 subunit,leading to improved lipid metabolism and insulin sensitization in mice. |
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V121023 | O-304 sodium | O-304 sodium is a first-in-class, orally bioavailable pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. | |
|
V3110 | PF-06409577 | 1467057-23-3 | PF-06409577 (PF06409577) is a potent, selective, orally bioavailable, allosteric activator ofAMPKα1β1γ1 (5′ adenosine monophosphate-activated protein kinase) with the potential to be used for diabetic nephropathy. |