| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V97305 | (Rac)-Spirotetramat-enol | 382608-09-5 | (Rac)-Spirotetramat-enol (Compound 8) is a ligand for acetyl-CoA carboxylase and can be used to synthesize PROTAC ADC degraders. |
|
V2852 | CP640186 HCl | 591778-70-0 | CP-640186 HCl is a novel and potent inhibitor of mammalian ACCs (isozyme-nonselective acetyl-CoA carboxylase) with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; It hash improved metabolic stability in comparison to CP-610431, an analog of CP-640186. |
|
V2050 | CP640186 | 591778-68-6 | CP-640186 is a novel, potent and and cell-permeableinhibitor of mammalian ACCs (isozyme-nonselective acetyl-CoA carboxylase) with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; It hash improved metabolic stability in comparison to CP-610431, an analog of CP-640186. |
|
V2798 | Firsocostat (ND-630; GS-0976; NDI-010976) | 1434635-54-7 | Firsocostat (formerly also known as ND-630; GS-0976; NDI-010976; ND630) is a novel and potent inhibitor of ACC (acetyl-CoA carboxylase) with IC50 values of 2.1 and 6.1 nM for human ACC1 and ACC2, respectively. |
|
V3778 | Firsocostat (S enantiomer) | 2128714-16-7 | ND-630 S enantiomer, the S enantiomer of ND-630 (also known as GS-0976; NDI-010976; firsocostat), is a potent inhibitor of ACC (acetyl-CoA carboxylase). |
|
V4302 | MK-4074 | 1039758-22-9 | MK-4074 is a novel, potent and liver-specific inhibitor ofacetyl-CoA carboxylaseACC1 and ACC2 which are enzymes that produce malonyl-CoA for fatty acid synthesis, withIC50values of 3 nM. |
|
V145223 | Spirotetramat-enol | 203312-38-3 | Spirotetramat-enol is a metabolite of spirotetramat (3) and is an insecticide. |
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