| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V96728 | (S)-HexylHIBO | 334887-48-8 | (S)-HexylHIBO is the S-enantiomer of HexylHIBO. |
|
V104823 | 1-Benzyl-APDC | 171336-76-8 | 1-Benzyl-APDC is a mGluR6 agonist in CHO cells with EC50 of 20 μM. |
|
V77221 | AZD 2066 hydrate | AZD 2066 hydrate is a selective, orally bioactive and BBB (blood-brain barrier) permeable/penetrable mGluR5 antagonist. | |
|
V92296 | Desmethyl-YM-298198 | 299901-57-8 | Desmethyl-YM-298198 is a high affinity, selective, noncompetitive mGluR1 antagonist (IC50: 16 nM). |
|
V21041 | FITM | 932737-65-0 | FITM is a negative allosteric modulator (NAM) of the mGlu1 receptor with Ki of 2.5 nM. |
|
V2921 | JNJ-40411813 | 1127498-03-6 | JNJ-40411813 (formerly known as ADX71149) is a novel positive allosteric modulator of the mGlu2R receptor (metabotropic Glutamate 2 receptor) with EC50 of 147 nM. |
|
V2844 | JNJ-42153605 | 1254977-87-1 | JNJ-42153605 is a potent, selective and allosteric modulator of the mGlu2 (metabotropic glutamate 2) receptor with with an EC50 of 17 nM. |
|
V4655 | Lu AF21934 | 1445605-23-1 | Lu AF21934 is a novel, potent, selective and brain-penetrant positive allosteric modulator of mGlu4 receptors with an IC50 of 500 nM for human mGlu4 |
|
V70624 | (RS)-MCPG Disodium Salt | 1303994-09-3 | MCPG is a carboxyphenylglycine. |
|
V86671 | mGluR2 agonist 1 | mGluR2 agonist 1 (Compound 5b) is a potent and selective metabotropic glutamate 2 receptor (mGluR) agonist with EC50 of 82 nM. | |
|
V83371 | mGluR2 agonist 1 hydrochloride | ||
|
V70600 | mGluR2 antagonist 1 | 1432728-49-8 | mGluR2 antagonist 1 is an orally bioactive, BBB (blood-brain barrier) permeable/penetrable, selective negative allosteric modulator (NAM) of mGluR2 (IC50 is 9 nM). |
|
V70618 | mGluR5 antagonist-1 | 2761424-76-2 | mGluR5antagonist-1 is a high-affinity mGluR5 antagonist (inhibitor) with IC50 of 11.5 nM. |
|
V70601 | MGS0274 | 1501974-69-1 | MGS0274 is a lipophilic precursor of the mGlu2 and mGlu3 receptor agonist MGS0008, which improves oral bioavailability (F). |
|
V70616 | trans-ACPD (Trans-(±)-ACP) | 67684-64-4 | trans-ACPD is a metabotropic receptor agonist (activator) that promotes calcium ion activity and generates inward current. |
|
V102519 | UBP 1112 | 339526-74-8 | UBP 1112 is a selective group III mGluR antagonist with a Kd of 5.1 μM, which is 96-fold more selective than group II mGlu receptors (Kd, 488 μM), while having no significant effect on group I mGlu receptors and iGlu receptors. |
|
V70607 | VU0364770 hydrochloride | 1414842-70-8 | VU0364770 HCl is a potent and specific mGlu4 PAM (positive allosteric modulator). |
|
V147050 | VU6024945 | VU6024945 is an orally effective metabolizing glutamate receptor subtype 5 (mGlu5 NAM) negative allosteric modulator with an IC50 value of 110 nM. | |
|
V147052 | VU6031545 | 3107596-27-7 | VU6031545 is a potent mGlu 5 negative allosteric modifier with an IC50 of 15 nM. |
|
V147053 | VU6033685 | VU6033685 is an orally effective mGlu1 positive allosteric modulator (PAM) that positively modulates human mGlu1 and human mGlu5, with EC50 values of 39 nM and 3960 nM, respectively. |
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