Raf

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Raf

Raf related products

Cat No.	Product Name	CAS No.	Product Description
V1009	ZM 336372	208260-29-1	ZM 336372 (ZM-336372; ZM336372) is a novel, potent and selective c-Raf kinase inhibitor with potential anticancer activity.
V2761	AD80	1384071-99-1	AD80 is a novel multikinase inhibitor that shows strong activity against human RET, BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR.
V1013	Agerafenib (CEP-32496; RXDX-105; AC013773)	1188910-76-0	Agerafenib (formerly RXDX105; AC013773;RXDX-105;CEP-32496;AC-01377)is a potent and orally bioactive inhibitor of BRAFV600E and c-Raf with potential antitumor activity.
V1006	AZ 628 (AZ-628; AZ628)	878739-06-1	AZ-628 (AZ628; AZ 628) is a novel, selective, and orally bioavailable Raf inhibitor with potential antineoplastic activity.
V4710	BI-882370	1392429-79-6	BI-882370 (BI 882370), structurally similar to vermurafenib, is a novel, highly potent and selective BRAF inhibitor with anticancer activity.
V99901	Brimarafenibum	1643326-82-2	Brimarafenib is a rapidly accelerating fibrosarcoma (Raf) kinase inhibitor with antitumor effects.
V2661	CCT196969	1163719-56-9	CCT196969 (CCT-196969) is a novel, orally bioavailable, pan-RAF inhibitor (IC50 = 0.1 μM) with anti-SRC and anticancer activity.
V134934	EGFR/BRAFV600E-IN-4		EGFR/BRAFV600E-IN-4 is a dual inhibitor of EGFR and BRAFV600E, with IC50 values of 61 nM and 43 nM, respectively.
V1005	GDC-0879	905281-76-7	GDC-0879 (AR-00341677;GDC-0879; AR00341677) is a novel, potent, highly selective, and orally bioavailable B-Raf kinase inhibitor with potential antitumor activity.
V1011	GW5074	220904-83-6	GW5074 (GW-5074; GW 5074) is a novel, potent and selective c-Raf inhibitor with potential neuroprotective activity.
V80402	ISIS 5132 sodium (CGP 69846A sodium; ISIS 9271 sodium)		ISIS 5132sodium is an oligonucleotide that specifically downregulates c-raf expression.
V138097	ISIS 5132 sodium scrambled negative control		The ISIS 5132 sodium scrambled negative control is a negative control with the sequence of ISIS 5132 sodium salt scrambled.
V97885	LSN3074753	1455031-68-1	LSN3074753 is a LY3009120-class drug that is a pan-RAF and Raf dimer inhibitor.
V4222	LUT-014	2274819-46-2	LUT014 is a novel, potent and topical B-Raf Inhibitor which is a proprietary, first-in-class, small molecule allowing administration of EGFR (Epidermal Growth Factor Receptor) Inhibitors to patients without interruptions caused by typical cutaneous side effects.
V1015	LY3009120 (DP-4978)	1454682-72-4	LY03009120 (DP4978;LY-3009120;LY-03009120;DP-4978) is a novel and potent pan-Raf inhibitor with potential anticancer activity.
V1007	NVP-BHG712 (BHG712)	940310-85-0	NVP-BHG712 (NVP BHG-712;NVP BHG712;BHG-712) is a selective and orally bioavailable EphB4 inhibitor with potential anticancer activity.
V1002	PLX-4720	918505-84-7	PLX4720 (PLX-4720; PLX 4720), a 7-azaindole/pyrrolopyridine-based vemurafenib derivative discovered by a structure-guided discovery approach, is a novel, potent and selective inhibitor of B-RafV600E mutant with potential antitumor activity.
V2666	PLX7904	1393465-84-3	PLX7904 (also known as PLX-7904; PB04; PB-04) is a novel potent and selective paradox-breaker B-Raf inhibitor with anticancer activity.
V117622	RAF1 YDYD Recombinant Human Active Protein Kinase		Ras-related factor 1 (RAF1) belongs to the RAF protein kinase family, also known as C-Raf.
V2920	RAF709	1628838-42-5	RAF709 is a novel and potent inhibitor of the Raf kinase B/C isoforms (compound example 131 from patent WO2014151616A1) developed through a hypothesis-driven approach focusing on drug-like properties.