| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0727 | Danoprevir ( ITMN191, R7227; RO5190591; RG7227) | 850876-88-9 | Danoprevir (formerly ITMN-191, R-7227; RO-5190591; RG 7227; RG-7227; trade name Ganovo) is an orally bioavailable and15-membered macrocyclic peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50s in the range of 0.2-3.5 nM. |
|
V3702 | Elbasvir | 1370468-36-2 | Elbasvir (formerly known as MK-8742; MK8742; trade name Zepatier) is a potent NS5A (nonstructural protein 5A) inhibitor with anti-HCV (hepatitis C virus) activities against different HCV genotypes. |
|
V2976 | Paritaprevir | 1216941-48-8 | Paritaprevir (formerly ABT-450; ABT450;Veruprevir; Viekirax;Viekira Pak; Technivie) is an acylsulfonamide analog and a component of the anti-HCV drug combination therapies: Viekira Pak (Paritaprevir+ombitasvir, ritonavir and dasabuvir) and Technivie (Paritaprevir+ombitasvir and ritonavir). |
|
V3157 | Boceprevir (EBP-520; SCH-503034) | 394730-60-0 | Boceprevir (previously known as EBP 520; SCH 503034; trade name: Victrelis) is a novel, orally bioavailable, selective, direct acting inhibitor ofhepatitis C virus (HCV) protease with Ki value of 14 nM for NS3 in an enzyme assay andEC90of 350 nM in cell-based replicon assay. |
|
V0725 | Telaprevir ( LY-570310; VX950; MP-424) | 402957-28-2 | Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM. |
|
V0726 | Lomibuvir | 1026785-55-6 | Lomibuvir (also called VX-22; S-1480; VCH222; VX22; S1480; VX222; VCH-222; VX-222) is a novel, potent and selective non-nucleoside inhibitor/NNI of hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase with IC50s in the range of 0.94-1.2 μM. |
|
V3154 | Simeprevir | 923604-59-5 | Simeprevir (previously known asTMC43) is a competitive, reversible, macrocyclic, noncovalent inhibitor of the hepatitis C virus (HCV) NS3/4A protease. |
|
V0724 | Daclatasvir (BMS790052; EBP883) | 1009119-64-5 | Daclatasvir (formerly BMS-790052; EBP-883; trade name Daklinza), adirect-acting antiviral agent, is aselective inhibitor of HCV NS5A (nonstructural protein) with an EC50 of 9-50 pM. |