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HCV Protease

HCV Protease

HCV Protease related products

Structure Cat No. Product Name CAS No. Product Description
丹诺普韦 V0727 Danoprevir ( ITMN191, R7227; RO5190591; RG7227) 850876-88-9 Danoprevir (formerly ITMN-191, R-7227; RO-5190591; RG 7227; RG-7227; trade name Ganovo) is an orally bioavailable and15-membered macrocyclic peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50s in the range of 0.2-3.5 nM.
依巴司韦 V3702 Elbasvir 1370468-36-2 Elbasvir (formerly known as MK-8742; MK8742; trade name Zepatier) is a potent NS5A (nonstructural protein 5A) inhibitor with anti-HCV (hepatitis C virus) activities against different HCV genotypes.
帕利普韦 V2976 Paritaprevir 1216941-48-8 Paritaprevir (formerly ABT-450; ABT450;Veruprevir; Viekirax;Viekira Pak; Technivie) is an acylsulfonamide analog and a component of the anti-HCV drug combination therapies: Viekira Pak (Paritaprevir+ombitasvir, ritonavir and dasabuvir) and Technivie (Paritaprevir+ombitasvir and ritonavir).
波普瑞韦 V3157 Boceprevir (EBP-520; SCH-503034) 394730-60-0 Boceprevir (previously known as EBP 520; SCH 503034; trade name: Victrelis) is a novel, orally bioavailable, selective, direct acting inhibitor ofhepatitis C virus (HCV) protease with Ki value of 14 nM for NS3 in an enzyme assay andEC90of 350 nM in cell-based replicon assay.
特拉匹伟 V0725 Telaprevir ( LY-570310; VX950; MP-424) 402957-28-2 Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM.
罗米布韦 V0726 Lomibuvir 1026785-55-6 Lomibuvir (also called VX-22; S-1480; VCH222; VX22; S1480; VX222; VCH-222; VX-222) is a novel, potent and selective non-nucleoside inhibitor/NNI of hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase with IC50s in the range of 0.94-1.2 μM.
西米普韦 V3154 Simeprevir 923604-59-5 Simeprevir (previously known asTMC43) is a competitive, reversible, macrocyclic, noncovalent inhibitor of the hepatitis C virus (HCV) NS3/4A protease.
达卡他韦 V0724 Daclatasvir (BMS790052; EBP883) 1009119-64-5 Daclatasvir (formerly BMS-790052; EBP-883; trade name Daklinza), adirect-acting antiviral agent, is aselective inhibitor of HCV NS5A (nonstructural protein) with an EC50 of 9-50 pM.
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