| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V94239 | AG-13958 (mono(hydrochloride)) | 319463-49-5 | AG-13958 monohydrochloride is a potent VEGFR tyrosine kinase inhibitor used to study choroidal neovascularization in age-related macular degeneration (AMD). |
|
V129311 | APX004 | APX004 is a humanized monoclonal antibody that targets VEGF2. | |
|
V69455 | CP-547632 TFA | 2805804-54-8 | CP-547632 TFA is an orally bioactive, ATP-competitive inhibitor of VEGFR-2 and FGF kinases with IC50s of 11 nM and 9 nM, respectively. |
|
V112721 | EG01449 | EG01449 is a quinoline neurocilione-1 (NRP1) antagonist with a Kd value of 0.6 µM. | |
|
V106026 | Eutypenes I | Eutypenes I (compound 9) inhibits the secretion of VEGF-A and the activation of VEGFR and its downstream Erk/Akt signaling pathway. | |
|
V87343 | hCA/VEGFR-2-IN-5 | hCA/VEGFR-2-IN-5 (compound 9) is an indole-based benzenesulfonamide and a potential dual inhibitor of cancer-related hCA IX/XII and VEGFR-2, with IC50 values of 0.38 μM, 40 and 3.2 nM for VEGFR-2, hCA IX and hCA XII, respectively. | |
|
V139156 | LY3022856 | LY3022856 is a humanized antibody expressed in CHO cells that targets VEGFR3/FLT4. | |
|
V140443 | MSB-0254 | MSB-0254 is a humanized monoclonal antibody (mAb) targeting VEGFR2/KDR/CD309. | |
|
V114451 | RC148 | RC148 is a humanized IgG1 bispecific antibody that targets VEGF and PD-1. | |
|
V69641 | Rhamnazin | 552-54-5 | Rhamnazin is an orally bioactive VEGFR2 signaling pathway inhibitor (antagonist) with IC50 of 4.68 μM for VEGFR2 kinase. |
|
V69638 | Suvemcitug | 1610010-57-5 | Suvemcitug is an IgG1κ antibody targeting VEGF developed from African hare (Oryctolagus cuniculus). |
|
V106449 | Tovecimig | Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4. | |
|
V88060 | VEGFR-2-IN-44 | 288144-20-7 | VEGFR-2-IN-44 (compound 4b) is a selective VEGF-R2 (Flk-1) inhibitor with IC50 of 70 nM. |
|
V146911 | VEGFR-2-IN-65 | 371213-22-8 | VEGFR-2-IN-65 is a VEGFR-2 inhibitor. |
|
V116694 | VEGFR-2-IN-76 | VEGFR-2-IN-76 (compound GL-3) is a potent VEGFR-2 inhibitor with an IC50 value of 5.44 μM. |