| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V73184 | (R)-IDO/TDO-IN-1 | 2033173-00-9 | (R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor (antagonist) with good pharmacokinetic properties. |
|
V114631 | Amg-1 | 496023-55-3 | Amg-1 is a potent, reversible, and selective inhibitor of indoleamine 2,3-dioxygenase (IDO1) (IC50 = 3.0 μM). |
|
V87527 | AT-0174 | AT-0174 is an orally active dual inhibitor of IDO1/TDO2 (tryptophan 2,3-dioxygenase-2) with IC50 values of 0.17 and 0.25 μM, respectively. | |
|
V87525 | IDO1-IN-24 | IDO1-IN-24 (compound 2c) inhibits the production of IDO1 in cell-based assays with an IC50 value of 17 μM. | |
|
V97638 | IDO1-IN-25 | 2841467-86-3 | IDO1-IN-25 is a dual IDO1/TDO2 inhibitor with IC50 values of 0.17 μM and 3.2 μM, respectively. |
|
V51702 | IDO1/2-IN-1 | 2310286-45-2 | IDO1/2-IN-1 is the first effective dual reduction of IDO1/IDO2, with IC50 of 28 nM and 144 nM for IDO1 and IDO2, respectively. |
|
V0940 | INCB024360 analogue (IDO5L) | 914471-09-3 | INCB024360 analog (Epacadostat analog; INCB-024360 analog; IDO-IN-2), a hydroxyamidine-based compound, is an orally bioavailable and competitive inhibitor of IDO1 (indoleamine-(2,3)-dioxygenase) with potential immunomodulating and anticancer activities. |
|
V24280 | LM10 | 1316695-35-8 | LM10 is a novel, potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) with IC50 values of 0.62 and 2 μM for human and mouse TDO, respectively. |
|
V0939 | NLG919 | 1402836-58-1 | NLG919 analog (RG6078 analog; GDC-0919 analog; GDC0919 analog; IDO-IN-7; NLG-919 analog) is a novel, potent and orally bioavailable inhibitor of IDO (indoleamine-(2,3)-dioxygenase) pathway with potential immunomodulating and antitumor activity. |
|
V119628 | Pronqodine A | 1424195-39-0 | Pronqodine A is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 value of 131.5 nM. |
|
V145700 | TDO-IN-2 | TDO-IN-2 is an orally effective TDO inhibitor (IC50: 1.25 μM). | |
|
V145699 | TDO2-IN-1 | TDO2-IN-1 is a selective TDO2 inhibitor. | |
|
V94676 | VS-15 | 951948-78-0 | VS-15 is an IDO1 inhibitor that selectively binds to the heme-free form of IDO1. |
|
V147204 | XW-032 | XW-032 is an apo-IDO1 inhibitor with an IC50 of 21 nM. | |
|
V0941 | Indoximod (NLG 8189) | 110117-83-4 | Indoximod (1-Methyl-D-tryptophan) is an orally bioactive indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. |
|
V0942 | Epacadostat (INCB024360) | 1204669-58-8 | Epacadostat (formerly INCB024360;IDO-IN-1;INCB-024360; INCB-24360; INCB24360) is an orally bioavailable, potent and selective IDO1(indoleamine-(2,3)-dioxygenase) inhibitor with potential immunomodulating and antitumor activity. |
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