| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V67546 | 3,7-DMF | 20950-52-1 | 3,7-DMF is an orally bioavailable inhibitor of TGF-β1-induced HSC activation. |
|
V67566 | Myristoyl tetrapeptide-12 | 959610-24-3 | Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the association of SMAD3 with DNA. |
|
V106443 | Rilogrotug | Rilogrotug is an IgG1κ human antibody directed against GDF15. | |
|
V2956 | SIS3 HCl | 521984-48-5 | SIS3 HCl is a potent and selective inhibitor of Smad3 which is a receptor-regulated intracellular protein that functions downstream of TGF-β and activin receptors and mediates their signaling, playing a role in cell proliferation, differentiation, apoptosis and formation of extracellular matrix. |
|
V87618 | TAT-QFNP12 | TAT-QFNP12 blocks NDRG2-PPM1A binding and reduces Smad2/3 phosphorylation, diminishing astrocyte MMP-9 production and blood-brain barrier disruption after subarachnoid hemorrhage (SAH). | |
|
V118587 | TAT-QFNP12 acetate | TAT-QFNP12 acetate is a polypeptide that blocks NDRG2-PPM1A binding and reduces Smad2/3 phosphorylation, thereby reducing MMP-9 production in astrocytes and reducing blood-brain barrier disruption after subarachnoid hemorrhage (SAH). | |
|
V118989 | TGF-β/Smad-IN-2 | TGF-β/Smad-IN-2 is an orally effective TGF-β/Smad inhibitor. | |
|
V3718 | TP0427736 | 864374-00-5 | TP0427736 is a novel, potent and selective inhibitor ofALK5 kinase with IC50 value of 2.72 nM andappropriate in vitro and in vivo profiles. |