| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V1504 | PF-543 | 1415562-82-1 | PF-543 (also called PF543; PF 543; Sphingosine Kinase 1 Inhibitor II) is a novel cell-permeable and sphingosine-competitive inhibitor of SphK1 with potential antitumor activity. |
|
V1503 | SKI II | 312636-16-1 | SKI II (also known as SphK-I2; Sphingosine kinase inhibitor II; SK-III) is a potent, highly selective, non-lipid and non-ATP-competitive sphingosine kinase (SphK) inhibitor with potential anticancer activity. |
|
V1506 | Opaganib (ABC294640) | 915385-81-8 | Opaganib (formerly known as ABC294640; ABC-294640; Trade name Yeliva) is a novel, potent, selective, competitive and orally bioavailable aryladamantane analog and selective sphingosine kinase-2 (SphK2) inhibitor with potential anticancer activity. |
|
V1507 | Ozanimod (RPC1063) | 1306760-87-1 | Ozanimod (formerly RPC-1063; trade name Zeposia) is a selective and orally bioavailable S1P Receptor 1 modulator that has been approved as an immunomodulatory medication for the treatment of relapsing multiple sclerosis and ulcerative colitis. |
|
V1502 | Fingolimod (FTY720) HCl | 162359-56-0 | Fingolimod HCl (formerly FTY-720; FTY 720; Gilenia and Gilenya), an FDA approved drug for the treatment of Multiple sclerosis, is a S1P (sphingosine 1-phosphate) antagonist with potential antineoplastic activity. |
|
V1505 | Siponimod (BAF312) | 1230487-00-9 | Siponimod (BAF-312; WHO-9491; NVP-BAF-312; Mayzent) is anovel, potent and orally bioavailable S1P receptor modulator with immunomodulating activity. |