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RET

RET

RET related products

Structure Cat No. Product Name CAS No. Product Description
AST487 (NVP- AST487) V3376 AST487 (NVP- AST487) 630124-46-8 AST487 (also known as NVP- AST487) is a novel and potent inhibitor of RET kinase with anticancer activity.
Pralsetinib (BLU 667) V4830 Pralsetinib (BLU 667) 2097132-94-8 Pralsetinib (GAVRETO; BLU667; BLU-667) is a novel, highly potent, selective, FDA approved RET inhibitor with anticancer activity.
RET G810R Recombinant Human Active Protein Kinase V118829 RET G810R Recombinant Human Active Protein Kinase Transfection rearrangement (RET) is a transmembrane receptor protein tyrosine kinase (PTK).
RET Ligand-Linker Conjugate-1 V144043 RET Ligand-Linker Conjugate-1 RET Ligand-Linker Conjugate-1 is a conjugate composed of RET ligands and linkers.
RET-IN-26 V79251 RET-IN-26 RET-IN-26 (compound D5) is a RET kinase inhibitor (antagonist) with IC50 of 0.33 μM.
RET-IN-29 V144045 RET-IN-29 RET-IN-29 is a selective RET kinase inhibitor.
RET-IN-5 V69545 RET-IN-5 2725770-20-5 RET-IN-5 is a potent RET inhibitor (antagonist) with IC50 of 4.57 nM (WO2021213476A1, compound 18).
YW-N-7 TFA V147268 YW-N-7 TFA YW-N-7 TFA is a PROTAC that targets and inhibits the degradation of RET kinase, with a DC50 of 88 nM.
Zeteletinib hemiadipate (BOS-172738 hemiadipate; DS-5010 hemiadipate) V69535 Zeteletinib hemiadipate (BOS-172738 hemiadipate; DS-5010 hemiadipate) 2375837-06-0 Zeteletinib (BOS-172738; DS-5010) hemiadipate is an orally bioactive, selective RET kinase inhibitor (antagonist) with nanomolar potency for RET and >300-fold selectivity for VEGFR2.
ZW-6-052 V110742 ZW-6-052 ZW-6-052 (compound 20) is a derivative of ZW-18-116 and is a dual-target PROTAC degrader that can degrade the oncoproteins TRKA and RET.
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