| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V3376 | AST487 (NVP- AST487) | 630124-46-8 | AST487 (also known as NVP- AST487) is a novel and potent inhibitor of RET kinase with anticancer activity. |
|
V4830 | Pralsetinib (BLU 667) | 2097132-94-8 | Pralsetinib (GAVRETO; BLU667; BLU-667) is a novel, highly potent, selective, FDA approved RET inhibitor with anticancer activity. |
|
V118829 | RET G810R Recombinant Human Active Protein Kinase | Transfection rearrangement (RET) is a transmembrane receptor protein tyrosine kinase (PTK). | |
|
V144043 | RET Ligand-Linker Conjugate-1 | RET Ligand-Linker Conjugate-1 is a conjugate composed of RET ligands and linkers. | |
|
V79251 | RET-IN-26 | RET-IN-26 (compound D5) is a RET kinase inhibitor (antagonist) with IC50 of 0.33 μM. | |
|
V144045 | RET-IN-29 | RET-IN-29 is a selective RET kinase inhibitor. | |
|
V69545 | RET-IN-5 | 2725770-20-5 | RET-IN-5 is a potent RET inhibitor (antagonist) with IC50 of 4.57 nM (WO2021213476A1, compound 18). |
|
V147268 | YW-N-7 TFA | YW-N-7 TFA is a PROTAC that targets and inhibits the degradation of RET kinase, with a DC50 of 88 nM. | |
|
V69535 | Zeteletinib hemiadipate (BOS-172738 hemiadipate; DS-5010 hemiadipate) | 2375837-06-0 | Zeteletinib (BOS-172738; DS-5010) hemiadipate is an orally bioactive, selective RET kinase inhibitor (antagonist) with nanomolar potency for RET and >300-fold selectivity for VEGFR2. |
|
V110742 | ZW-6-052 | ZW-6-052 (compound 20) is a derivative of ZW-18-116 and is a dual-target PROTAC degrader that can degrade the oncoproteins TRKA and RET. |