CFTR

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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CFTR

CFTR related products

Cat No.	Product Name	CAS No.	Product Description
V96736	(R)-Crinecerfont	2649012-21-3	(R)-Crinecerfont is the R isomer of Crinecerfont.
V97850	CFTR corrector 15	1170387-92-4	CFTR Corrector 15 (Compound 4172) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) that, when combined with VX-809, can repair the F508del-CFTR folding defect.
V97466	CFTR corrector 16	1210305-23-9	CFTR calibrator 16 (Compound 39) is a calibrator of the cystic fibrosis transmembrane conductance regulator (CFTR) and can be used in the study of cystic fibrosis.
V87136	IDOR-4	2839901-24-3	IDOR-4 is a type IV CFTR corrector.
V106262	kCAL01	1364717-03-2	kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM.
V2875	PPQ-102	931706-15-9	PPQ-102 (also known as CFTR Inhibitor) is a potentinhibitor of CFTR (cystic fibrosis transmembrane conductance regulator) discovered from screening of approximately 110000 small synthetic and natural compounds for inhibition of halide influx in CFTR-expressing epithelial cells.
V3314	PTI-428	1953130-87-4	PTI-428 is a novel, potent CFTR amplifier being developed byProteostasis Therapeutics, Inc.
V147045	VU439		VU439 is a functionalized photoaffinity ligand for Elexacaftor.
V3551	FDL-169	1628416-28-3	FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) correctorbeing developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation, the most common mutation in this disease.