| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V3738 | CZC-25146 | 1191911-26-8 | CZC-25146 is a potent, selective, and metabolically stable LRRK2 inhibitor (Leucine-rich repeat kinase-2) with IC50 of 4.76 nM and 6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively. |
|
V3739 | CZC-25146 HCl | 1191911-26-8 | CZC-25146 is a potent, selective, and metabolically stable LRRK2 inhibitor (Leucine-rich repeat kinase-2) with IC50 of 4.76 nM and 6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively. |
|
V2923 | CZC-54252 | 1191911-27-9 | CZC-54252 is a potent, selective, and metabolically stable LRRK2 inhibitor (Leucine-rich repeat kinase-2) with IC50 of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively. |
|
V0773 | GNE-7915 | 1351761-44-8 | GNE-7915 (GNE 7915; GNE7915) is a novel,highly potent, selective, and brain-penetrant leucine-rich repeat kinase 2 (LRRK2) inhibitor with anti-PD (Parkinsons disease) activity. |
|
V3835 | GNE-7915 tosylate | 2070015-00-6 | GNE-7915 tosylate is a novel,highly potent, selective, and brain-penetrant leucine-rich repeat kinase 2 (LRRK2) inhibitor, with IC50 and Ki of 9 nM and 1 nM, respectively. |
|
V0774 | GNE-9605 | 1536200-31-3 | GNE-9605 (GNE 9605; GNE9605) is a novel, brain-penetrant,highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with anti-PD (Parkinsons disease) activity. |
|
V0775 | GSK2578215A | 1285515-21-0 | GSK2578215A (GSK-2578215A; GSK 2578215A;GSK-2578215 A) is a novel, highly potent and selective LRRK2 kinase inhibitor with anti-PD (Parkinsons disease) activity. |
|
V88563 | LRRK2-IN-13 | 3032733-17-5 | LRRK2-IN-13 (Compound 13) is an inhibitor of LRRK2 (IC50=0.57 nM). |
|
V0776 | LRRK2-IN-1 | 1234480-84-2 | LRRK2-IN-1 (LRRK2-IN 1; LRRK2 IN-1) is a novel, highly potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2) with anti-PD (Parkinsons disease) activity. |
|
V98092 | Nictide | 1159973-22-4 | Nictide is a peptide substrate of LRRK2 (leucine-rich repeat protein kinase 2). |
|
V2916 | PF-06447475 | 1527473-33-1 | PF-06447475 (PF06447475) is a novel, highly potent, selective and brain penetrable inhibitor ofLeucine rich repeat kinase 2 (LRRK2)with anti-PD activity. |
|
V144232 | RN277 | RN277 is an LRRK2 type II kinase inhibitor. | |
|
V144233 | RN341 | RN341 is a specific type II kinase inhibitor that inhibits the activity of LRRK2 (IC50: 296 nM). | |
|
V145256 | SRI-31255 | 905580-86-1 | SRI-31255 is an orally effective LRRK2 inhibitor with IC50 values of 520 nM for wild-type (WT) and 427 nM for mutant G2019S. |