Lipoxygenase

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Lipoxygenase

Lipoxygenase related products

Cat No.	Product Name	CAS No.	Product Description
V87583	(±)15-HEDE	77159-57-0	(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE.
V102788	15(S)-HEDE	92693-04-4	15(S)-HEDE (Compound 8) is an analog of 15-HEDE and inhibits 5-lipoxygenase with IC50 of 26 μM.
V124961	3-(4-Hydroxy-3-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one	104236-73-9	3-(4-Hydroxy-3-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one is a selective lipid peroxidation inhibitor.
V73506	3-O-Acetyl-11-hydroxy-beta-boswellic acid (3α-O-acetyl-11α-hydroxy-beta-boswellic acid)	146019-25-2	3-O-Acetyl-11-hydroxy-beta-boswellic acid is a 5-lipoxygenase (5-LO) inhibitor.
V131453	CGS 24891	134823-10-2	CGS 24891 is an orally effective 5-lipoxygenase (5-LO) inhibitor with an IC50 value of 0.051 μM in guinea pigs and 0.11 μM in dogs.
V138379	KC-11404	148490-22-6	KC-11404 is an orally effective antihistamine and 5-lipoxygenase inhibitor with an IC50 value of 0.9 μM against guinea pig 5-lipoxygenase.
V3027	ML355	1532593-30-8	ML355 is the first selective, orally bioavailable 12-LOX inhibitor which displays high potency (IC50 of 0.34 μM) against 12-LOX and excellent selectivity over related lipoxygenases and cyclooxygenases.
V144425	Ruthenoleuton		Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM.
V145198	Speranskoside	219917-70-1	Speranskoside is a dual COX-2/15-LOX inhibitor with a COX-2 IC50 of 2.62 μg/mL and a 15-LOX IC50 of 5.51 μg/mL.
V147154	WY-50295	123016-21-7	WY-50295 is an orally effective selective 5-lipoxygenase inhibitor.
V29841	β-Boswellic acid	631-69-6	β-Boswellic acid is extracted from the gum resin of Boswellia serrate.
V10619	AKBA (Acetyl-11-keto-β-boswellic acid)	67416-61-9	AKBA,an active triterpenoid isolated from Boswellia serrate,is an antiangiogenic and neuroprotective agent as well asa novel Nrf2 activator.
V2108	Zileuton (A 64077; Abbott 64077)	111406-87-2	Zileuton (also known as A-64077;Abbott 64077; ZYFLO; ZYFLO CR)is a novel, potent and orally bioactive inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, it was introduced in 1996 to decrease the symptoms of asthma.