GPR

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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GPR

GPR related products

Cat No.	Product Name	CAS No.	Product Description
V70558	[Ala17]-MCH	359784-84-2	[Ala17]-MCH is an analog of MCH and is a ligand for MCHR1 (Ki=0.16 nM) with greater selectivity for MCHR2 (Ki=34 nM).
V1806	AZD1981	802904-66-1	AZD1981 is a novel potent and selective CRTh2 (Chemoattractant receptor-homologous molecule expressed on TH2 cells; DP2-Prostaglandin D2 receptor 2, ) receptor antagonist with IC50 of 4 nM,it displayed>1000-fold selectivity over more than 340 other enzymes and receptors, including DP1.
V135144	EP-3945	3057176-00-5	EP-3945 is a potent Mas-associated G protein-coupled receptor (MRGPR) agonist, which is more potent than the MRGPRD small molecule agonist β-alanine.
V93588	Gpr35 modulator 1	2994189-01-2	Gpr35 modulator 1 (compound 1-18) is a potent modulator of Gpr35 with IC50 ≤100 nM in HEK293 cells stably transfected with human GPR35.
V1803	Fasiglifam (TAK875)	1000413-72-8	Fasiglifam(formerly known as TAK-875; TAK875) is a novel, long-acting, selective and orally bioavailable GPR40 agonist with anti-diabetic activity.
V136879	GPR84 agonist-2	3105662-82-3	GPR84 agonist-2 is a selective GPR84 agonist that is inactive against free fatty acid receptors.
V1804	GSK1292263	1032823-75-8	GSK1292263 is a novel and potentGPR119 (G-protein-coupled receptor 119) agonist whichhas potential for the treatment of type 2 diabetes.
V1805	GW9508	885101-89-3	GW9508 is a novel, potent and selective agonist for FFA1 (fatty acid receptor GPR40) with pEC50 of 7.32, and is 100-fold selective against GPR120, it stimulates insulin secretion in a glucose-sensitive manner.
V140403	MrgprX2-IN-2	2792205-87-7	MrgprX2-IN-2 is a selective Mas-associated G protein-coupled receptor X2 (MRGPRX2) antagonist.
V144075	RGH-706	2027497-52-3	RGH-706 is an orally effective, selective MCH1 receptor antagonist that crosses the blood-brain barrier, with an IC50 value of 6.2 nM for hMCHR1.
V144403	RTI-122 dihydrochloride		RTI-122 dihydrochloride is a selective, blood-brain barrier-crossing GPR88 agonist (cAMP EC50 = 11 nM), with EC50 values of 11.5 nM and 155 nM for human and mouse GPR88, respectively ([35S]GTPγS assay).
V144654	SB-583355	3040121-49-8	SB-583355 is a potent G2A antagonist.
V144809	Setomagpran	2991434-57-0	Setomagpran is an antagonist of mas-associated G protein-coupled receptors (MRGPR) and has anti-inflammatory activity.
V1807	Timapiprant (OC000459)	851723-84-7	Timapiprant (formerly known as OC000459; OC-000459) is a novel, potent, selective, and orally bioactive prostanoid receptor 2 (DP2- also known as CRTH2)) antagonist with IC50 of 13 nM.
V146185	TMN-OMe		TMN-OMe is a GPR39 agonist that can cross the blood-brain barrier and is also a radiotracer used in positron emission tomography (PET).
V70308	Zelatriazin (TAK-041; NBI-1065846)	1929519-13-0	Zelatriazin (TAK-041; NBI-1065846) is a potent and specific GPR139 agonist/activator with EC50 of 22 nM.