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BCRP

BCRP

BCRP related products

Structure Cat No. Product Name CAS No. Product Description
ABCG2-IN-4 V105029 ABCG2-IN-4 2559759-63-4 ABCG2-IN-4 (compound K31) is an orally available ABCG2 inhibitor that reduces the release of protoporphyrin IX (PPIX) from erythrocytes into plasma and prevents phototoxicity.
ABCG2-IN-5 V117213 ABCG2-IN-5 190323-50-3 ABCG2-IN-5 (compound 10) is a selective ABCG2 inhibitor with an IC50 value of 0.34 µM.
Ac22(Az8)2 V115602 Ac22(Az8)2 2377858-65-4 Ac22(Az8)2 is a selective BCRP inhibitor (EC50: 1-2 nM).
Ac32Az19 V74159 Ac32Az19 2760674-72-2 Ac32Az19 is a potent, nontoxic, and selective BCRP inhibitor (antagonist) with EC50 of 13 nM in BCRP-overexpressing HEK293/R2 cells.
KS176 V3037 KS176 1253452-78-6 KS176 is a novel potent and highly selective/specific inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter with IC50 values of 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively.
RG 14620 V13718 RG 14620 136831-49-7 RG 14620 (RG-14620),a non-phenolic tyrphostin analog, is a novel and potent EGFR inhibitor (IC50 = 3 μM) with anticancer activity.
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