| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V118458 | (1R,2R)-Elpipodect | 1424378-99-3 | (1R,2R)-Elpipodect ((1R,2R)-MK-8189) is the (1R,2R) type enantiomer of Elpipodect. |
|
V3497 | (R)-(-)-Rolipram | 85416-75-7 | R)-(-)-Rolipram is the R-enantiomer of Rolipram with potent anti-inflammatory and anti-depressant activity in the central nervous system, and it is more potent than its S enantiomer. |
|
V4097 | 3-Isobutyl-1-methylxanthine | 28822-58-4 | IBMX is anonspecific, broad-spectrum, competitive inhibitor of phosphodiesterase (PDE) inhibitor, withIC50s of 6.5, 26.3 and 31.7 μM forPDE3,PDE4andPDE5, respectively. |
|
V102752 | 4-Nitrophenyl phenylphosphonate | 57072-35-2 | 4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. |
|
V72046 | Autotaxin-IN-6 | 2800898-98-8 | Autotaxin-IN-6 (compound 23) is an autotaxin (ATX) inhibitor (antagonist) with IC50 of 30 nM. |
|
V3770 | BI-409306 | 1189767-28-9 | BI 409306 (SUB 166499) isa novel potent, selective and oral phosphodiesterase 9A (PDE9A)inhibitor. |
|
V72079 | Braylin | 6054-10-0 | Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammation and immunomodulation, making it a potential target for studying immuno-inflammatory diseases. |
|
V4092 | BRL-50481 | 433695-36-4 | BRL-50481 is a novel, potent and selective inhibitor ofphosphodiesterase 7(PDE7) withIC50s of 0.15, 12.1, 62 and 490 μM forPDE7A,PDE7B,PDE4andPDE3, respectively. |
|
V72017 | Deltasonamide 2 hydrochloride | 2448341-55-5 | Deltasonamide 2 HCl is a competitive, high-affinity inhibitor of PDEδ with Kd of ~385 pM. |
|
V87666 | Denbufylline | 57076-71-8 | Denbufylline (BRL 30892) is a phosphodiesterase-4 (PDE4) inhibitor. |
|
V4471 | Edelinontrine (PF-04447943) | 1082744-20-4 | PF-04447943 (PF04447943) is a novel and potent inhibitor of human recombinantPDE9A with the potential for the treatment of cognitive disorders. |
|
V87665 | endo CNTinh-03 | 345288-49-5 | Endo CNTinh-03 inhibits the increase in cAMP and cGMP induced by agonists of G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 of 4 μM). |
|
V87003 | Enpp-1-IN-20 | Enpp-1-IN-20 (Compound 31) is an ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor with an IC50 of 0.09 nM. | |
|
V103606 | Enpp-1-IN-21 | 2803505-78-2 | Enpp-1-IN-21 (compound 4g) is an ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor with IC50 of 0.45 and 0.19 μM for ENPP1 and ENPP3, respectively. |
|
V70270 | Etazolate hydrochloride (SQ 20009; EHT 0202 hydrochloride) | 35838-58-5 | Etazolate HCl (SQ 20009) is an orally bioactive and selective inhibitor of phosphodiesterase type 4 (PDE4) with IC50 of 2 μM. |
|
V72025 | Gisadenafil besylate (UK 369003-26) | 334827-98-4 | Gisadenafil besylate (UK 369003-26) is a specific, orally bioactive phosphodiesterase 5 (PDE5) inhibitor (antagonist) with IC50 of 3.6 nM that prevents the degradation of cyclic guanosine monophosphate (cGMP). |
|
V101202 | MDL3 | MDL3 is a novel PDE4B and PDE5A inhibitor. | |
|
V102159 | Menabitan | 83784-21-8 | Menabitan (SP-204) is a phosphodiesterase 9 (PDE 9) inhibitor that acts as a non-opioid analgesic. |
|
V119883 | Nelvutamig | 3029433-56-2 | Nelvutamig is a humanized immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) antibody that targets ENPP3/CD203c and CD3E. |
|
V87673 | PDE1-IN-7 | 3027833-49-1 | PDE1-IN-7 (Compound 13h) is a selective inhibitor of bPDE1 (IC50=10 nM). |
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