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E1 E2 E3 Enzyme

E1 E2 E3 Enzyme

E1 E2 E3 Enzyme related products

Structure Cat No. Product Name CAS No. Product Description
Apazunersen sodium V116801 Apazunersen sodium Apazulsen sodium is an antisense oligonucleotide that targets and inhibits the expression of the UBE3A antisense transcript (UBE3A-AS), thereby preventing the silencing of the paternal allele in the UBE3A gene and reactivating the expression of the defective protein.
BC-1293 V99658 BC-1293 1219395-86-4 BC-1293 is an inhibitor of the E3 ligase subunit FBXO24.
Cbl-b-IN-10 V73102 Cbl-b-IN-10 2815225-12-6 Cbl-b-IN-10 (Compound 463) is an inhibitor (blocker/antagonist) of casitas b lineage lymphoma (Cbl-b) and c-Cbl? with IC50 of 6.0 nM and 3.5 nM respectively.
Cbl-b-IN-29 V111015 Cbl-b-IN-29 3070411-10-5 Cbl-b-IN-29 is an orally effective CBL-B inhibitor.
Cbl-b-IN-7 V73104 Cbl-b-IN-7 2815221-35-1 Cbl-b-IN-7 (Compound 248) is an inhibitor (blocker/antagonist) of casitas b lineage lymphoma (Cbl-b) and c-Cbl? with IC50 of 6.7 nM and 5.2 nM respectively.
DCN1-UBC12-IN-4 V107005 DCN1-UBC12-IN-4 26028-65-9 DCN1-UBC12-IN-4 (compound 5p) is an inhibitor of DCN1-UBC12 with IC50＞10000 nM and exhibits antitumor activity.
DI-1548 V117317 DI-1548 2247060-97-3 DI-1548 is a potent, selective, and irreversible covalent inhibitor of DCN1 (IC50 = 4.6 nM).
HOIPIN-8 V76922 HOIPIN-8 HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with IC50 of 11 nM.
ML307 V83672 ML307
Obudanersen sodium scrambled negative control V141768 Obudanersen sodium scrambled negative control The Obudanersen sodium scrambled negative control is a negative control for Obudanersen sodium with a scrambled sequence.
Rugonersen sodium scrambled negative control V144420 Rugonersen sodium scrambled negative control The Rugonersen sodium scrambled negative control is a negative control for Rugonersen sodium with a scrambled sequence.
SENP1-IN-3 V73100 SENP1-IN-3 2416910-59-1 SENP1-IN-3 is an inhibitor (blocker/antagonist) of the specific de-SUMOylation protease SENP1.
Skp2 inhibitor 2 V73084 Skp2 inhibitor 2 2760612-77-7 Skp2 inhibitor 2 (14f) is an inhibitor (blocker/antagonist) of the F-box protein S-phase kinase-related protein 2 (Skp2) with IC50 of 10.2 μM (Skp2-Cks1).
Smurf-1-IN-3 V145073 Smurf-1-IN-3 1825312-08-0 Smurf-1-IN-3 is a selective Smurf-1 inhibitor with an IC50 value of 2.2 nM.
Smurf1-IN-5 V145074 Smurf1-IN-5 1824647-09-7 Smurf1-IN-5 is an allosteric SMAD ubiquitin regulator 1 (SMURF1) inhibitor.
SPI-05 V145213 SPI-05 5463-64-9 SPI-05 is a non-competitive SUMO-specific protease (SENP1/2) inhibitor (IC50 = 60 μM).
TRIM25 ligand-1 V146475 TRIM25 ligand-1 3111776-36-1 TRIM25 ligand-1 is a covalent ligand.
UBE2T/FANCL-IN-1 V73089 UBE2T/FANCL-IN-1 1359415-02-3 UBE2T/FANCL-IN-1 is a potent inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitination and sensitizes cells to the DNA cross-linker carboplatin.
WSB1 Degrader 1 V73092 WSB1 Degrader 1 2306039-66-5 WSB1 Degrader 1 is a potent orally bioactive WSB1 (WD repeat and SOCS box-containing 1) degrader.
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