| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V111536 | (E)-Belizatinib | 1388225-72-6 | (E)-Belitazartinib ((E)-TSR-011) (compound 36) is the (E)-isomer of belitazartinib, a potent, selective, and orally effective anaplastic lymphoma kinase (ALK) inhibitor with an enzymatic IC50 of 0.005 μM and a cellular IC50 of 0.048 μM. |
|
V110318 | ALK/HDAC-IN-2 | ALK/HDAC-IN-2 (compound 19b) is an ALK/HDAC inhibitor with IC₅₀ values of 8 nM for wild-type ALK and 1.18 μM for all HDACs. | |
|
V128534 | ALK5-IN-86 | ALK5-IN-86 is a selective ALK5 inhibitor with an IC50 value of 0.267 μM. | |
|
V131234 | CDD-1115 | 3034215-86-3 | CDD-1115 is a potent and selective BMPR2 inhibitor with an IC50 of 1.8 nM and 6.2 nM for Kiapp. |
|
V138720 | LDN-193688 | 1062368-51-7 | LDN-193688 is an ALK2 inhibitor with IC₅₀ values of 104, 18, 235, 1530, and 1080 nM for ALK1, ALK2, ALK3, ALK4, and ALK5, respectively. |
|
V108935 | PROTAC EML4-ALK Degrader-2 | 2417174-28-6 | PROTAC EML4-ALK Degrader-2 is an EML4-ALK PROTAC degrader. |
|
V18838 | X-376 | 1365267-27-1 | X-376 (an analog ofEnsartinib or X-396) is a novel, potent and highly selectiveALK inhibitor with IC50of 0.61 nM and the potential to be used for treating non-small cell lung cancer. |