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ALK

ALK

ALK related products

Structure Cat No. Product Name CAS No. Product Description
(E)-Belizatinib V111536 (E)-Belizatinib 1388225-72-6 (E)-Belitazartinib ((E)-TSR-011) (compound 36) is the (E)-isomer of belitazartinib, a potent, selective, and orally effective anaplastic lymphoma kinase (ALK) inhibitor with an enzymatic IC50 of 0.005 μM and a cellular IC50 of 0.048 μM.
ALK/HDAC-IN-2 V110318 ALK/HDAC-IN-2 ALK/HDAC-IN-2 (compound 19b) is an ALK/HDAC inhibitor with IC₅₀ values of 8 nM for wild-type ALK and 1.18 μM for all HDACs.
ALK5-IN-86 V128534 ALK5-IN-86 ALK5-IN-86 is a selective ALK5 inhibitor with an IC50 value of 0.267 μM.
CDD-1115 V131234 CDD-1115 3034215-86-3 CDD-1115 is a potent and selective BMPR2 inhibitor with an IC50 of 1.8 nM and 6.2 nM for Kiapp.
LDN-193688 V138720 LDN-193688 1062368-51-7 LDN-193688 is an ALK2 inhibitor with IC₅₀ values of 104, 18, 235, 1530, and 1080 nM for ALK1, ALK2, ALK3, ALK4, and ALK5, respectively.
PROTAC EML4-ALK Degrader-2 V108935 PROTAC EML4-ALK Degrader-2 2417174-28-6 PROTAC EML4-ALK Degrader-2 is an EML4-ALK PROTAC degrader.
X-376 V18838 X-376 1365267-27-1 X-376 (an analog ofEnsartinib or X-396) is a novel, potent and highly selectiveALK inhibitor with IC50of 0.61 nM and the potential to be used for treating non-small cell lung cancer.
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